2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-isopropoxy-phenyl)-3H-quinazolin-4-one (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-isopropoxy-phenyl)-3H-quinazolin-4-one's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-isopropoxy-phenyl)-3H-quinazolin-4-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MT1E Gene (Entity type)	0.01078373
2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-isopropoxy-phenyl)-3H-quinazolin-4-one Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	KM-03949SC Compound (Entity type)	0.2123860120773315
2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-isopropoxy-phenyl)-3H-quinazolin-4-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TFF3 Gene (Entity type)	0.010916592
2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-isopropoxy-phenyl)-3H-quinazolin-4-one Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	CGP53353 Compound (Entity type)	0.2381511479616165
2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-isopropoxy-phenyl)-3H-quinazolin-4-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	RRAGD Gene (Entity type)	0.0089838365
2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-isopropoxy-phenyl)-3H-quinazolin-4-one Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Gastrin/cholecystokinin type B receptor Protein (Entity type)	IC50
2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-isopropoxy-phenyl)-3H-quinazolin-4-one Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MSMO1 Gene (Entity type)	-0.008539495
2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-isopropoxy-phenyl)-3H-quinazolin-4-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CHAC1 Gene (Entity type)	0.008815626
2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-isopropoxy-phenyl)-3H-quinazolin-4-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TUBB2B Gene (Entity type)	0.009237079
2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-isopropoxy-phenyl)-3H-quinazolin-4-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MT1H Gene (Entity type)	0.008444939

2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-isopropoxy-phenyl)-3H-quinazolin-4-one
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MT1E
Gene (Entity type)
0.01078373

2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-isopropoxy-phenyl)-3H-quinazolin-4-one
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
KM-03949SC
Compound (Entity type)
0.2123860120773315

2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-isopropoxy-phenyl)-3H-quinazolin-4-one
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TFF3
Gene (Entity type)
0.010916592

2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-isopropoxy-phenyl)-3H-quinazolin-4-one
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
CGP53353
Compound (Entity type)
0.2381511479616165

2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-isopropoxy-phenyl)-3H-quinazolin-4-one
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
RRAGD
Gene (Entity type)
0.0089838365

2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-isopropoxy-phenyl)-3H-quinazolin-4-one
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Gastrin/cholecystokinin type B receptor
Protein (Entity type)
IC50

2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-isopropoxy-phenyl)-3H-quinazolin-4-one
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MSMO1
Gene (Entity type)
-0.008539495

2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-isopropoxy-phenyl)-3H-quinazolin-4-one
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CHAC1
Gene (Entity type)
0.008815626

2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-isopropoxy-phenyl)-3H-quinazolin-4-one
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TUBB2B
Gene (Entity type)
0.009237079

2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-isopropoxy-phenyl)-3H-quinazolin-4-one
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MT1H
Gene (Entity type)
0.008444939

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