5-(4-amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)benzo[d]oxazol-2-amine (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 5-(4-amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)benzo[d]oxazol-2-amine's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
5-(4-amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)benzo[d]oxazol-2-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	NAT1 Gene (Entity type)	-0.014758252
5-(4-amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)benzo[d]oxazol-2-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ASNS Gene (Entity type)	-0.013531047
5-(4-amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)benzo[d]oxazol-2-amine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NT5E Gene (Entity type)	0.017952379
5-(4-amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)benzo[d]oxazol-2-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PHGDH Gene (Entity type)	-0.019950174
5-(4-amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)benzo[d]oxazol-2-amine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DKK1 Gene (Entity type)	0.014725593
5-(4-amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)benzo[d]oxazol-2-amine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SLC25A6 Gene (Entity type)	0.014724097
(5-(2-((2R,6S)-2,6-dimethylmorpholino)-4-morpholinopyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	5-(4-amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)benzo[d]oxazol-2-amine Compound (Entity type)	0.8233805894851685
dactolisib Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	5-(4-amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)benzo[d]oxazol-2-amine Compound (Entity type)	0.9216917157173156
5-(4-amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)benzo[d]oxazol-2-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DDIT4 Gene (Entity type)	-0.025411014
5-(4-amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)benzo[d]oxazol-2-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MLLT11 Gene (Entity type)	-0.013810482

5-(4-amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)benzo[d]oxazol-2-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
NAT1
Gene (Entity type)
-0.014758252

5-(4-amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)benzo[d]oxazol-2-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ASNS
Gene (Entity type)
-0.013531047

5-(4-amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)benzo[d]oxazol-2-amine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
NT5E
Gene (Entity type)
0.017952379

5-(4-amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)benzo[d]oxazol-2-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PHGDH
Gene (Entity type)
-0.019950174

5-(4-amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)benzo[d]oxazol-2-amine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
DKK1
Gene (Entity type)
0.014725593

5-(4-amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)benzo[d]oxazol-2-amine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SLC25A6
Gene (Entity type)
0.014724097

(5-(2-((2R,6S)-2,6-dimethylmorpholino)-4-morpholinopyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
5-(4-amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)benzo[d]oxazol-2-amine
Compound (Entity type)
0.8233805894851685

dactolisib
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
5-(4-amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)benzo[d]oxazol-2-amine
Compound (Entity type)
0.9216917157173156

5-(4-amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)benzo[d]oxazol-2-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
DDIT4
Gene (Entity type)
-0.025411014

5-(4-amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)benzo[d]oxazol-2-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MLLT11
Gene (Entity type)
-0.013810482

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