2-[2-(6-Methyl-benzo[1,3]dioxol-5-yl)-acetyl]-thiophene-3-sulfonic acid (4-chloro-3-methyl-isoxazol-5-yl)-amide (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 2-[2-(6-Methyl-benzo[1,3]dioxol-5-yl)-acetyl]-thiophene-3-sulfonic acid (4-chloro-3-methyl-isoxazol-5-yl)-amide's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
2-[2-(6-Methyl-benzo[1,3]dioxol-5-yl)-acetyl]-thiophene-3-sulfonic acid (4-chloro-3-methyl-isoxazol-5-yl)-amide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HOPX Gene (Entity type)	0.0070042126
2-[2-(6-Methyl-benzo[1,3]dioxol-5-yl)-acetyl]-thiophene-3-sulfonic acid (4-chloro-3-methyl-isoxazol-5-yl)-amide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PEG10 Gene (Entity type)	-0.0072629014
2-[2-(6-Methyl-benzo[1,3]dioxol-5-yl)-acetyl]-thiophene-3-sulfonic acid (4-chloro-3-methyl-isoxazol-5-yl)-amide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	RARRES2 Gene (Entity type)	-0.0049103433
2-[2-(6-Methyl-benzo[1,3]dioxol-5-yl)-acetyl]-thiophene-3-sulfonic acid (4-chloro-3-methyl-isoxazol-5-yl)-amide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CXCL12 Gene (Entity type)	0.0052114152
2-[2-(6-Methyl-benzo[1,3]dioxol-5-yl)-acetyl]-thiophene-3-sulfonic acid (4-chloro-3-methyl-isoxazol-5-yl)-amide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PLTP Gene (Entity type)	0.005510237
2-[2-(6-Methyl-benzo[1,3]dioxol-5-yl)-acetyl]-thiophene-3-sulfonic acid (4-chloro-3-methyl-isoxazol-5-yl)-amide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NDUFA4L2 Gene (Entity type)	0.004298268
2-[2-(6-Methyl-benzo[1,3]dioxol-5-yl)-acetyl]-thiophene-3-sulfonic acid (4-chloro-3-methyl-isoxazol-5-yl)-amide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CLGN Gene (Entity type)	-0.0045428383
2-[2-(6-Methyl-benzo[1,3]dioxol-5-yl)-acetyl]-thiophene-3-sulfonic acid (4-chloro-3-methyl-isoxazol-5-yl)-amide Compound (Entity type)	Indication Knowledge Graph Relation (Entity type)	Pulmonary arterial hypertension Disease or Phenotype (Entity type)
2-[2-(6-Methyl-benzo[1,3]dioxol-5-yl)-acetyl]-thiophene-3-sulfonic acid (4-chloro-3-methyl-isoxazol-5-yl)-amide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	STK10 Gene (Entity type)	-0.0047736643
2-[2-(6-Methyl-benzo[1,3]dioxol-5-yl)-acetyl]-thiophene-3-sulfonic acid (4-chloro-3-methyl-isoxazol-5-yl)-amide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	GNAI1 Gene (Entity type)	-0.0047648274

2-[2-(6-Methyl-benzo[1,3]dioxol-5-yl)-acetyl]-thiophene-3-sulfonic acid (4-chloro-3-methyl-isoxazol-5-yl)-amide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
HOPX
Gene (Entity type)
0.0070042126

2-[2-(6-Methyl-benzo[1,3]dioxol-5-yl)-acetyl]-thiophene-3-sulfonic acid (4-chloro-3-methyl-isoxazol-5-yl)-amide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PEG10
Gene (Entity type)
-0.0072629014

2-[2-(6-Methyl-benzo[1,3]dioxol-5-yl)-acetyl]-thiophene-3-sulfonic acid (4-chloro-3-methyl-isoxazol-5-yl)-amide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
RARRES2
Gene (Entity type)
-0.0049103433

2-[2-(6-Methyl-benzo[1,3]dioxol-5-yl)-acetyl]-thiophene-3-sulfonic acid (4-chloro-3-methyl-isoxazol-5-yl)-amide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CXCL12
Gene (Entity type)
0.0052114152

2-[2-(6-Methyl-benzo[1,3]dioxol-5-yl)-acetyl]-thiophene-3-sulfonic acid (4-chloro-3-methyl-isoxazol-5-yl)-amide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PLTP
Gene (Entity type)
0.005510237

2-[2-(6-Methyl-benzo[1,3]dioxol-5-yl)-acetyl]-thiophene-3-sulfonic acid (4-chloro-3-methyl-isoxazol-5-yl)-amide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
NDUFA4L2
Gene (Entity type)
0.004298268

2-[2-(6-Methyl-benzo[1,3]dioxol-5-yl)-acetyl]-thiophene-3-sulfonic acid (4-chloro-3-methyl-isoxazol-5-yl)-amide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CLGN
Gene (Entity type)
-0.0045428383

2-[2-(6-Methyl-benzo[1,3]dioxol-5-yl)-acetyl]-thiophene-3-sulfonic acid (4-chloro-3-methyl-isoxazol-5-yl)-amide
Compound (Entity type)
Indication
Knowledge Graph Relation (Entity type)
Pulmonary arterial hypertension
Disease or Phenotype (Entity type)

2-[2-(6-Methyl-benzo[1,3]dioxol-5-yl)-acetyl]-thiophene-3-sulfonic acid (4-chloro-3-methyl-isoxazol-5-yl)-amide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
STK10
Gene (Entity type)
-0.0047736643

2-[2-(6-Methyl-benzo[1,3]dioxol-5-yl)-acetyl]-thiophene-3-sulfonic acid (4-chloro-3-methyl-isoxazol-5-yl)-amide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
GNAI1
Gene (Entity type)
-0.0047648274

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