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COXFA4L2 (Gene)

Ensembl Gene ID: ENSG00000185633

Entrez Gene ID: 56901

Description: cytochrome c oxidase hypoxia associated subunit FA4L2

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View COXFA4L2's neighborhood in the knowledge graph.

Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with COXFA4L2.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using COXFA4L2.

GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for COXFA4L2.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with COXFA4L2.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

This repository is under review for potential modification in compliance with Administration directives.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	ARG-TC-41 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	COXFA4L2 Gene (Entity type)	-0.009777998
	fenthion Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	COXFA4L2 Gene (Entity type)	0.0047998354
	pirinixic acid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	COXFA4L2 Gene (Entity type)	-0.0095750885
	KFGENEBIN:NDUFA4L2-variant-count CUI KFGENEBIN (Entity type)	Gene has variants Knowledge Graph Relation (Entity type)	COXFA4L2 Gene (Entity type)
	cromakalim Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	COXFA4L2 Gene (Entity type)	-0.009085944
	2-[2-(6-Methyl-benzo[1,3]dioxol-5-yl)-acetyl]-thiophene-3-sulfonic acid (4-chloro-3-methyl-isoxazol-5-yl)-amide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	COXFA4L2 Gene (Entity type)	0.004298268
	MR-16728 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	COXFA4L2 Gene (Entity type)	-0.009301664
	perospirone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	COXFA4L2 Gene (Entity type)	0.012160063
	Nitrendipine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	COXFA4L2 Gene (Entity type)	-0.0024659513
	T0156 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	COXFA4L2 Gene (Entity type)	0.0055036317

ARG-TC-41
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
COXFA4L2
Gene (Entity type)
-0.009777998

fenthion
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
COXFA4L2
Gene (Entity type)
0.0047998354

pirinixic acid
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
COXFA4L2
Gene (Entity type)
-0.0095750885

KFGENEBIN:NDUFA4L2-variant-count CUI
KFGENEBIN (Entity type)
Gene has variants
Knowledge Graph Relation (Entity type)
COXFA4L2
Gene (Entity type)

cromakalim
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
COXFA4L2
Gene (Entity type)
-0.009085944

2-[2-(6-Methyl-benzo[1,3]dioxol-5-yl)-acetyl]-thiophene-3-sulfonic acid (4-chloro-3-methyl-isoxazol-5-yl)-amide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
COXFA4L2
Gene (Entity type)
0.004298268

MR-16728
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
COXFA4L2
Gene (Entity type)
-0.009301664

perospirone
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
COXFA4L2
Gene (Entity type)
0.012160063

Nitrendipine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
COXFA4L2
Gene (Entity type)
-0.0024659513

T0156
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
COXFA4L2
Gene (Entity type)
0.0055036317

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