3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	RANBP1 Gene (Entity type)	0.0041044853
3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	RAB11FIP1 Gene (Entity type)	-0.0032886683
3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	RHOBTB3 Gene (Entity type)	0.004840743
3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PDLIM3 Gene (Entity type)	0.0033680315
3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IGFBP5 Gene (Entity type)	0.003774576
3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PGAM1 Gene (Entity type)	0.004195819
3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ZNF395 Gene (Entity type)	0.0034426458
3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HMGB2 Gene (Entity type)	0.0050118635
3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	AK4 Gene (Entity type)	0.0032272318
3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Levonorgestrel Compound (Entity type)	0.3878070116043091

3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
RANBP1
Gene (Entity type)
0.0041044853

3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
RAB11FIP1
Gene (Entity type)
-0.0032886683

3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
RHOBTB3
Gene (Entity type)
0.004840743

3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PDLIM3
Gene (Entity type)
0.0033680315

3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
IGFBP5
Gene (Entity type)
0.003774576

3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PGAM1
Gene (Entity type)
0.004195819

3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ZNF395
Gene (Entity type)
0.0034426458

3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
HMGB2
Gene (Entity type)
0.0050118635

3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
AK4
Gene (Entity type)
0.0032272318

3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Levonorgestrel
Compound (Entity type)
0.3878070116043091

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