(2E,4E,6Z,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,4,6,8-tetraenoic acid (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View (2E,4E,6Z,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,4,6,8-tetraenoic acid's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
(2E,4E,6Z,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,4,6,8-tetraenoic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TXNDC9 Gene (Entity type)	0.010903276
(2E,4E,6Z,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,4,6,8-tetraenoic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Retinoic acid receptor alpha Protein (Entity type)
(2E,4E,6Z,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,4,6,8-tetraenoic acid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IGF2BP3 Gene (Entity type)	-0.008575475
(2E,4E,6Z,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,4,6,8-tetraenoic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DHRS3 Gene (Entity type)	0.008520095
(2E,4E,6Z,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,4,6,8-tetraenoic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SMAD3 Gene (Entity type)	0.010022253
(2E,4E,6Z,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,4,6,8-tetraenoic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NRIP1 Gene (Entity type)	0.00883957
(2E,4E,6Z,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,4,6,8-tetraenoic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Retinoic acid receptor RXR-beta Protein (Entity type)	EC50
Acitretin Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	(2E,4E,6Z,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,4,6,8-tetraenoic acid Compound (Entity type)	0.303528219461441
(2E,4E,6Z,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,4,6,8-tetraenoic acid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HMGCS1 Gene (Entity type)	-0.011016976
(2E,4E,6Z,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,4,6,8-tetraenoic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Retinoic acid receptor beta Protein (Entity type)	Ki

(2E,4E,6Z,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,4,6,8-tetraenoic acid
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TXNDC9
Gene (Entity type)
0.010903276

(2E,4E,6Z,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,4,6,8-tetraenoic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Retinoic acid receptor alpha
Protein (Entity type)

(2E,4E,6Z,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,4,6,8-tetraenoic acid
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
IGF2BP3
Gene (Entity type)
-0.008575475

(2E,4E,6Z,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,4,6,8-tetraenoic acid
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
DHRS3
Gene (Entity type)
0.008520095

(2E,4E,6Z,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,4,6,8-tetraenoic acid
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SMAD3
Gene (Entity type)
0.010022253

(2E,4E,6Z,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,4,6,8-tetraenoic acid
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
NRIP1
Gene (Entity type)
0.00883957

(2E,4E,6Z,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,4,6,8-tetraenoic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Retinoic acid receptor RXR-beta
Protein (Entity type)
EC50

Acitretin
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
(2E,4E,6Z,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,4,6,8-tetraenoic acid
Compound (Entity type)
0.303528219461441

(2E,4E,6Z,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,4,6,8-tetraenoic acid
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HMGCS1
Gene (Entity type)
-0.011016976

(2E,4E,6Z,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,4,6,8-tetraenoic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Retinoic acid receptor beta
Protein (Entity type)
Ki

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Knowledge Graph Assertions

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