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Retinoic acid receptor alpha (Protein)

Description: A protein in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Retinoic acid receptor alpha 's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	4-(3-hydroxy-3-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)prop-1-enyl)benzoic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Retinoic acid receptor alpha Protein (Entity type)
	4-[(E)-2-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-vinyl]-benzoic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Retinoic acid receptor alpha Protein (Entity type)	EC50
	4-(5-methyl-4-phenylthiazol-2-yl)benzoic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Retinoic acid receptor alpha Protein (Entity type)	EC50
	tretinoin Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Retinoic acid receptor alpha Protein (Entity type)	EC50
	tamibarotene Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Retinoic acid receptor alpha Protein (Entity type)	Ki
	4''-(acetylethylamino)-3''-tert-butyl-4'-(4-hydroxybutoxy)-[1,1';3',1'']terphenyl-4-carboxylic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Retinoic acid receptor alpha Protein (Entity type)	Kd
	6-[1-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-vinyl]-naphthalene-2-carboxylic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Retinoic acid receptor alpha Protein (Entity type)	Kd
	6-(3-isobutoxy-5-isopropoxybenzamido)nicotinic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Retinoic acid receptor alpha Protein (Entity type)	IC50
	4'-(4-hydroxybutoxy)-4''-pyrrolidin-1-yl-3''-trifluoromethyl[1,1';3,1'']terphenyl-4-carboxylic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Retinoic acid receptor alpha Protein (Entity type)	Kd
	4-[8-(4-Isopropyl-phenyl)-5,5-dimethyl-5,6-dihydro-naphthalen-2-ylethynyl]-benzoic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Retinoic acid receptor alpha Protein (Entity type)	Kd

4-(3-hydroxy-3-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)prop-1-enyl)benzoic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Retinoic acid receptor alpha
Protein (Entity type)

4-[(E)-2-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-vinyl]-benzoic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Retinoic acid receptor alpha
Protein (Entity type)
EC50

4-(5-methyl-4-phenylthiazol-2-yl)benzoic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Retinoic acid receptor alpha
Protein (Entity type)
EC50

tretinoin
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Retinoic acid receptor alpha
Protein (Entity type)
EC50

tamibarotene
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Retinoic acid receptor alpha
Protein (Entity type)
Ki

4''-(acetylethylamino)-3''-tert-butyl-4'-(4-hydroxybutoxy)-[1,1';3',1'']terphenyl-4-carboxylic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Retinoic acid receptor alpha
Protein (Entity type)
Kd

6-[1-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-vinyl]-naphthalene-2-carboxylic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Retinoic acid receptor alpha
Protein (Entity type)
Kd

6-(3-isobutoxy-5-isopropoxybenzamido)nicotinic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Retinoic acid receptor alpha
Protein (Entity type)
IC50

4'-(4-hydroxybutoxy)-4''-pyrrolidin-1-yl-3''-trifluoromethyl[1,1';3,1'']terphenyl-4-carboxylic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Retinoic acid receptor alpha
Protein (Entity type)
Kd

4-[8-(4-Isopropyl-phenyl)-5,5-dimethyl-5,6-dihydro-naphthalen-2-ylethynyl]-benzoic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Retinoic acid receptor alpha
Protein (Entity type)
Kd

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