(S)-2-(6-((2',6'-dimethyl-4'-(3-(methylsulfonyl)propoxy)biphenyl-3-yl)methoxy)-2,3-dihydrobenzofuran-3-yl)acetic acid (Compound)

Description: A compound in the knowledge graph

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View (S)-2-(6-((2',6'-dimethyl-4'-(3-(methylsulfonyl)propoxy)biphenyl-3-yl)methoxy)-2,3-dihydrobenzofuran-3-yl)acetic acid's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
(S)-2-(6-((2',6'-dimethyl-4'-(3-(methylsulfonyl)propoxy)biphenyl-3-yl)methoxy)-2,3-dihydrobenzofuran-3-yl)acetic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SPP1 Gene (Entity type)	0.0033478276
(S)-2-(6-((2',6'-dimethyl-4'-(3-(methylsulfonyl)propoxy)biphenyl-3-yl)methoxy)-2,3-dihydrobenzofuran-3-yl)acetic acid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	NVL Gene (Entity type)	-0.0037564305
(S)-2-(6-((2',6'-dimethyl-4'-(3-(methylsulfonyl)propoxy)biphenyl-3-yl)methoxy)-2,3-dihydrobenzofuran-3-yl)acetic acid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PEG10 Gene (Entity type)	-0.004390756
(S)-2-(6-((2',6'-dimethyl-4'-(3-(methylsulfonyl)propoxy)biphenyl-3-yl)methoxy)-2,3-dihydrobenzofuran-3-yl)acetic acid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DOCK9 Gene (Entity type)	-0.003467741
(S)-2-(6-((2',6'-dimethyl-4'-(3-(methylsulfonyl)propoxy)biphenyl-3-yl)methoxy)-2,3-dihydrobenzofuran-3-yl)acetic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Free fatty acid receptor 1 Protein (Entity type)	EC50
(S)-2-(6-((2',6'-dimethyl-4'-(3-(methylsulfonyl)propoxy)biphenyl-3-yl)methoxy)-2,3-dihydrobenzofuran-3-yl)acetic acid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CMAHP Gene (Entity type)	-0.0031497357
(S)-2-(6-((2',6'-dimethyl-4'-(3-(methylsulfonyl)propoxy)biphenyl-3-yl)methoxy)-2,3-dihydrobenzofuran-3-yl)acetic acid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IKZF1 Gene (Entity type)	-0.004632358
(S)-2-(6-((2',6'-dimethyl-4'-(3-(methylsulfonyl)propoxy)biphenyl-3-yl)methoxy)-2,3-dihydrobenzofuran-3-yl)acetic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	RPS4Y1 Gene (Entity type)	0.0048257187
(S)-2-(6-((2',6'-dimethyl-4'-(3-(methylsulfonyl)propoxy)biphenyl-3-yl)methoxy)-2,3-dihydrobenzofuran-3-yl)acetic acid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	NXN Gene (Entity type)	-0.0029859014
(S)-2-(6-((2',6'-dimethyl-4'-(3-(methylsulfonyl)propoxy)biphenyl-3-yl)methoxy)-2,3-dihydrobenzofuran-3-yl)acetic acid Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	darunavir Compound (Entity type)	0.2938819825649261

(S)-2-(6-((2',6'-dimethyl-4'-(3-(methylsulfonyl)propoxy)biphenyl-3-yl)methoxy)-2,3-dihydrobenzofuran-3-yl)acetic acid
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SPP1
Gene (Entity type)
0.0033478276

(S)-2-(6-((2',6'-dimethyl-4'-(3-(methylsulfonyl)propoxy)biphenyl-3-yl)methoxy)-2,3-dihydrobenzofuran-3-yl)acetic acid
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
NVL
Gene (Entity type)
-0.0037564305

(S)-2-(6-((2',6'-dimethyl-4'-(3-(methylsulfonyl)propoxy)biphenyl-3-yl)methoxy)-2,3-dihydrobenzofuran-3-yl)acetic acid
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PEG10
Gene (Entity type)
-0.004390756

(S)-2-(6-((2',6'-dimethyl-4'-(3-(methylsulfonyl)propoxy)biphenyl-3-yl)methoxy)-2,3-dihydrobenzofuran-3-yl)acetic acid
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
DOCK9
Gene (Entity type)
-0.003467741

(S)-2-(6-((2',6'-dimethyl-4'-(3-(methylsulfonyl)propoxy)biphenyl-3-yl)methoxy)-2,3-dihydrobenzofuran-3-yl)acetic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Free fatty acid receptor 1
Protein (Entity type)
EC50

(S)-2-(6-((2',6'-dimethyl-4'-(3-(methylsulfonyl)propoxy)biphenyl-3-yl)methoxy)-2,3-dihydrobenzofuran-3-yl)acetic acid
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CMAHP
Gene (Entity type)
-0.0031497357

(S)-2-(6-((2',6'-dimethyl-4'-(3-(methylsulfonyl)propoxy)biphenyl-3-yl)methoxy)-2,3-dihydrobenzofuran-3-yl)acetic acid
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
IKZF1
Gene (Entity type)
-0.004632358

(S)-2-(6-((2',6'-dimethyl-4'-(3-(methylsulfonyl)propoxy)biphenyl-3-yl)methoxy)-2,3-dihydrobenzofuran-3-yl)acetic acid
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
RPS4Y1
Gene (Entity type)
0.0048257187

(S)-2-(6-((2',6'-dimethyl-4'-(3-(methylsulfonyl)propoxy)biphenyl-3-yl)methoxy)-2,3-dihydrobenzofuran-3-yl)acetic acid
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
NXN
Gene (Entity type)
-0.0029859014

(S)-2-(6-((2',6'-dimethyl-4'-(3-(methylsulfonyl)propoxy)biphenyl-3-yl)methoxy)-2,3-dihydrobenzofuran-3-yl)acetic acid
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
darunavir
Compound (Entity type)
0.2938819825649261

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