N-(6-methoxy-5-(2-methoxyphenoxy)-2-(pyridin-4-yl)pyrimidin-4-yl)-5-methylpyridine-2-sulfonamide (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View N-(6-methoxy-5-(2-methoxyphenoxy)-2-(pyridin-4-yl)pyrimidin-4-yl)-5-methylpyridine-2-sulfonamide's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
N-(6-methoxy-5-(2-methoxyphenoxy)-2-(pyridin-4-yl)pyrimidin-4-yl)-5-methylpyridine-2-sulfonamide Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Rucaparib Compound (Entity type)	0.29328653216362
N-(6-methoxy-5-(2-methoxyphenoxy)-2-(pyridin-4-yl)pyrimidin-4-yl)-5-methylpyridine-2-sulfonamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CTSB Gene (Entity type)	-0.0044895657
N-(6-methoxy-5-(2-methoxyphenoxy)-2-(pyridin-4-yl)pyrimidin-4-yl)-5-methylpyridine-2-sulfonamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HOXC6 Gene (Entity type)	-0.004612238
N-(6-methoxy-5-(2-methoxyphenoxy)-2-(pyridin-4-yl)pyrimidin-4-yl)-5-methylpyridine-2-sulfonamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	S100A2 Gene (Entity type)	0.0049148537
N-(6-methoxy-5-(2-methoxyphenoxy)-2-(pyridin-4-yl)pyrimidin-4-yl)-5-methylpyridine-2-sulfonamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MFAP5 Gene (Entity type)	-0.0053687342
N-(6-methoxy-5-(2-methoxyphenoxy)-2-(pyridin-4-yl)pyrimidin-4-yl)-5-methylpyridine-2-sulfonamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	GOLGA8H Gene (Entity type)	-0.0043986063
N-(6-methoxy-5-(2-methoxyphenoxy)-2-(pyridin-4-yl)pyrimidin-4-yl)-5-methylpyridine-2-sulfonamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ISG15 Gene (Entity type)	0.0058964114
N-(6-methoxy-5-(2-methoxyphenoxy)-2-(pyridin-4-yl)pyrimidin-4-yl)-5-methylpyridine-2-sulfonamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ALOX5 Gene (Entity type)	0.0051451256
N-(6-methoxy-5-(2-methoxyphenoxy)-2-(pyridin-4-yl)pyrimidin-4-yl)-5-methylpyridine-2-sulfonamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	INHBA Gene (Entity type)	-0.004644331
N-(6-methoxy-5-(2-methoxyphenoxy)-2-(pyridin-4-yl)pyrimidin-4-yl)-5-methylpyridine-2-sulfonamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ID1 Gene (Entity type)	0.0054618125

N-(6-methoxy-5-(2-methoxyphenoxy)-2-(pyridin-4-yl)pyrimidin-4-yl)-5-methylpyridine-2-sulfonamide
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Rucaparib
Compound (Entity type)
0.29328653216362

N-(6-methoxy-5-(2-methoxyphenoxy)-2-(pyridin-4-yl)pyrimidin-4-yl)-5-methylpyridine-2-sulfonamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CTSB
Gene (Entity type)
-0.0044895657

N-(6-methoxy-5-(2-methoxyphenoxy)-2-(pyridin-4-yl)pyrimidin-4-yl)-5-methylpyridine-2-sulfonamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HOXC6
Gene (Entity type)
-0.004612238

N-(6-methoxy-5-(2-methoxyphenoxy)-2-(pyridin-4-yl)pyrimidin-4-yl)-5-methylpyridine-2-sulfonamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
S100A2
Gene (Entity type)
0.0049148537

N-(6-methoxy-5-(2-methoxyphenoxy)-2-(pyridin-4-yl)pyrimidin-4-yl)-5-methylpyridine-2-sulfonamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MFAP5
Gene (Entity type)
-0.0053687342

N-(6-methoxy-5-(2-methoxyphenoxy)-2-(pyridin-4-yl)pyrimidin-4-yl)-5-methylpyridine-2-sulfonamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
GOLGA8H
Gene (Entity type)
-0.0043986063

N-(6-methoxy-5-(2-methoxyphenoxy)-2-(pyridin-4-yl)pyrimidin-4-yl)-5-methylpyridine-2-sulfonamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ISG15
Gene (Entity type)
0.0058964114

N-(6-methoxy-5-(2-methoxyphenoxy)-2-(pyridin-4-yl)pyrimidin-4-yl)-5-methylpyridine-2-sulfonamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ALOX5
Gene (Entity type)
0.0051451256

N-(6-methoxy-5-(2-methoxyphenoxy)-2-(pyridin-4-yl)pyrimidin-4-yl)-5-methylpyridine-2-sulfonamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
INHBA
Gene (Entity type)
-0.004644331

N-(6-methoxy-5-(2-methoxyphenoxy)-2-(pyridin-4-yl)pyrimidin-4-yl)-5-methylpyridine-2-sulfonamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ID1
Gene (Entity type)
0.0054618125

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