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Rucaparib (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Rucaparib's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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Tools & Use Cases

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	N-(6-methoxy-5-(2-methoxyphenoxy)-2-(pyridin-4-yl)pyrimidin-4-yl)-5-methylpyridine-2-sulfonamide Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Rucaparib Compound (Entity type)	0.29328653216362
	Rucaparib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ALDH18A1 Gene (Entity type)	0.0040142364
	Rucaparib Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Poly [ADP-ribose] polymerase 2 Protein (Entity type)	IC50
	Rucaparib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CDKN1A Gene (Entity type)	0.0041271276
	Rucaparib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	AQP3 Gene (Entity type)	-0.006500398
	Rucaparib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TNFSF10 Gene (Entity type)	-0.0065692295
	Rucaparib Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Poly [ADP-ribose] polymerase 1 Protein (Entity type)	IC50
	Rucaparib Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Protein mono-ADP-ribosyltransferase PARP3 Protein (Entity type)	IC50
	Rucaparib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NOP16 Gene (Entity type)	0.0043107807
	Rucaparib Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	SID11114063 Compound (Entity type)	0.5927309989929199

N-(6-methoxy-5-(2-methoxyphenoxy)-2-(pyridin-4-yl)pyrimidin-4-yl)-5-methylpyridine-2-sulfonamide
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Rucaparib
Compound (Entity type)
0.29328653216362

Rucaparib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ALDH18A1
Gene (Entity type)
0.0040142364

Rucaparib
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Poly [ADP-ribose] polymerase 2
Protein (Entity type)
IC50

Rucaparib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CDKN1A
Gene (Entity type)
0.0041271276

Rucaparib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
AQP3
Gene (Entity type)
-0.006500398

Rucaparib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TNFSF10
Gene (Entity type)
-0.0065692295

Rucaparib
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Poly [ADP-ribose] polymerase 1
Protein (Entity type)
IC50

Rucaparib
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Protein mono-ADP-ribosyltransferase PARP3
Protein (Entity type)
IC50

Rucaparib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
NOP16
Gene (Entity type)
0.0043107807

Rucaparib
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
SID11114063
Compound (Entity type)
0.5927309989929199

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