5-(4-Chloro-phenyl)-6-ethyl-pyrimidine-2,4-diamine (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 5-(4-Chloro-phenyl)-6-ethyl-pyrimidine-2,4-diamine's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
5-(4-Chloro-phenyl)-6-ethyl-pyrimidine-2,4-diamine Compound (Entity type)	Indication Knowledge Graph Relation (Entity type)	Toxoplasmosis Disease or Phenotype (Entity type)
5-(4-Chloro-phenyl)-6-ethyl-pyrimidine-2,4-diamine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	EIF2S3 Gene (Entity type)	0.005155428
5-(4-Chloro-phenyl)-6-ethyl-pyrimidine-2,4-diamine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	RPS4Y1 Gene (Entity type)	0.005342817
5-(4-Chloro-phenyl)-6-ethyl-pyrimidine-2,4-diamine Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	methotrexate Compound (Entity type)	0.4252593517303467
5-(4-Chloro-phenyl)-6-ethyl-pyrimidine-2,4-diamine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	S100A8 Gene (Entity type)	-0.0051754247
5-(4-Chloro-phenyl)-6-ethyl-pyrimidine-2,4-diamine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	FASTKD5 Gene (Entity type)	-0.003955232
5-(4-Chloro-phenyl)-6-ethyl-pyrimidine-2,4-diamine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TENT5A Gene (Entity type)	-0.004246876
5-(4-Chloro-phenyl)-6-ethyl-pyrimidine-2,4-diamine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HSPA8 Gene (Entity type)	0.004415185
5-(4-Chloro-phenyl)-6-ethyl-pyrimidine-2,4-diamine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SUV39H1 Gene (Entity type)	0.0043519353
5-(4-Chloro-phenyl)-6-ethyl-pyrimidine-2,4-diamine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CASP10 Gene (Entity type)	-0.004489773

5-(4-Chloro-phenyl)-6-ethyl-pyrimidine-2,4-diamine
Compound (Entity type)
Indication
Knowledge Graph Relation (Entity type)
Toxoplasmosis
Disease or Phenotype (Entity type)

5-(4-Chloro-phenyl)-6-ethyl-pyrimidine-2,4-diamine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
EIF2S3
Gene (Entity type)
0.005155428

5-(4-Chloro-phenyl)-6-ethyl-pyrimidine-2,4-diamine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
RPS4Y1
Gene (Entity type)
0.005342817

5-(4-Chloro-phenyl)-6-ethyl-pyrimidine-2,4-diamine
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
methotrexate
Compound (Entity type)
0.4252593517303467

5-(4-Chloro-phenyl)-6-ethyl-pyrimidine-2,4-diamine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
S100A8
Gene (Entity type)
-0.0051754247

5-(4-Chloro-phenyl)-6-ethyl-pyrimidine-2,4-diamine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
FASTKD5
Gene (Entity type)
-0.003955232

5-(4-Chloro-phenyl)-6-ethyl-pyrimidine-2,4-diamine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TENT5A
Gene (Entity type)
-0.004246876

5-(4-Chloro-phenyl)-6-ethyl-pyrimidine-2,4-diamine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
HSPA8
Gene (Entity type)
0.004415185

5-(4-Chloro-phenyl)-6-ethyl-pyrimidine-2,4-diamine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SUV39H1
Gene (Entity type)
0.0043519353

5-(4-Chloro-phenyl)-6-ethyl-pyrimidine-2,4-diamine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CASP10
Gene (Entity type)
-0.004489773

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