(4-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-ylamino)phenyl)(4-(pyrrolidin-1-yl)piperidin-1-yl)methanone (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View (4-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-ylamino)phenyl)(4-(pyrrolidin-1-yl)piperidin-1-yl)methanone's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
(4-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-ylamino)phenyl)(4-(pyrrolidin-1-yl)piperidin-1-yl)methanone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	AKR1C2 Gene (Entity type)	0.00601503
(4-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-ylamino)phenyl)(4-(pyrrolidin-1-yl)piperidin-1-yl)methanone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	APOBEC3G Gene (Entity type)	-0.0064645247
(4-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-ylamino)phenyl)(4-(pyrrolidin-1-yl)piperidin-1-yl)methanone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ACKR3 Gene (Entity type)	0.008505438
(4-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-ylamino)phenyl)(4-(pyrrolidin-1-yl)piperidin-1-yl)methanone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SQLE Gene (Entity type)	0.006607451
(4-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-ylamino)phenyl)(4-(pyrrolidin-1-yl)piperidin-1-yl)methanone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MCOLN1 Gene (Entity type)	0.006475312
(4-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-ylamino)phenyl)(4-(pyrrolidin-1-yl)piperidin-1-yl)methanone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ADD3 Gene (Entity type)	-0.007057284
(4-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-ylamino)phenyl)(4-(pyrrolidin-1-yl)piperidin-1-yl)methanone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	BHLHE40 Gene (Entity type)	0.0059305686
(4-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-ylamino)phenyl)(4-(pyrrolidin-1-yl)piperidin-1-yl)methanone Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	SID11111534 Compound (Entity type)	0.4151994884014129
(4-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-ylamino)phenyl)(4-(pyrrolidin-1-yl)piperidin-1-yl)methanone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	AARS1 Gene (Entity type)	0.007304796
(4-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-ylamino)phenyl)(4-(pyrrolidin-1-yl)piperidin-1-yl)methanone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	KRT13 Gene (Entity type)	-0.0073472606

(4-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-ylamino)phenyl)(4-(pyrrolidin-1-yl)piperidin-1-yl)methanone
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
AKR1C2
Gene (Entity type)
0.00601503

(4-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-ylamino)phenyl)(4-(pyrrolidin-1-yl)piperidin-1-yl)methanone
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
APOBEC3G
Gene (Entity type)
-0.0064645247

(4-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-ylamino)phenyl)(4-(pyrrolidin-1-yl)piperidin-1-yl)methanone
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ACKR3
Gene (Entity type)
0.008505438

(4-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-ylamino)phenyl)(4-(pyrrolidin-1-yl)piperidin-1-yl)methanone
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SQLE
Gene (Entity type)
0.006607451

(4-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-ylamino)phenyl)(4-(pyrrolidin-1-yl)piperidin-1-yl)methanone
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MCOLN1
Gene (Entity type)
0.006475312

(4-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-ylamino)phenyl)(4-(pyrrolidin-1-yl)piperidin-1-yl)methanone
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ADD3
Gene (Entity type)
-0.007057284

(4-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-ylamino)phenyl)(4-(pyrrolidin-1-yl)piperidin-1-yl)methanone
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
BHLHE40
Gene (Entity type)
0.0059305686

(4-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-ylamino)phenyl)(4-(pyrrolidin-1-yl)piperidin-1-yl)methanone
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
SID11111534
Compound (Entity type)
0.4151994884014129

(4-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-ylamino)phenyl)(4-(pyrrolidin-1-yl)piperidin-1-yl)methanone
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
AARS1
Gene (Entity type)
0.007304796

(4-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-ylamino)phenyl)(4-(pyrrolidin-1-yl)piperidin-1-yl)methanone
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
KRT13
Gene (Entity type)
-0.0073472606

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