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Metergoline (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Metergoline's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	Metergoline Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Cytochrome P450 2D6 Protein (Entity type)	IC50
	Metergoline Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Sodium-dependent dopamine transporter Protein (Entity type)	Ki
	Metergoline Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	LDLR Gene (Entity type)	0.0040179775
	Metergoline Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DAXX Gene (Entity type)	-0.00381935
	N8-(3-Chloro-4-fluorophenyl)-N2-(1-methylpiperidin-4-yl)-pyrimido[5,4-d]pyrimidine-2,8-diamine Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Metergoline Compound (Entity type)	0.4390147030353546
	Metergoline Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Sodium-dependent serotonin transporter Protein (Entity type)	Ki
	Metergoline Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	FADS1 Gene (Entity type)	0.0059128166
	Metergoline Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	5-hydroxytryptamine receptor 1A Protein (Entity type)	EC50
	Metergoline Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SAMSN1 Gene (Entity type)	-0.0028797155
	Metergoline Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IL7R Gene (Entity type)	-0.0033355705

Metergoline
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Cytochrome P450 2D6
Protein (Entity type)
IC50

Metergoline
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Sodium-dependent dopamine transporter
Protein (Entity type)
Ki

Metergoline
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
LDLR
Gene (Entity type)
0.0040179775

Metergoline
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
DAXX
Gene (Entity type)
-0.00381935

N8-(3-Chloro-4-fluorophenyl)-N2-(1-methylpiperidin-4-yl)-pyrimido[5,4-d]pyrimidine-2,8-diamine
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Metergoline
Compound (Entity type)
0.4390147030353546

Metergoline
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Sodium-dependent serotonin transporter
Protein (Entity type)
Ki

Metergoline
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
FADS1
Gene (Entity type)
0.0059128166

Metergoline
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
5-hydroxytryptamine receptor 1A
Protein (Entity type)
EC50

Metergoline
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SAMSN1
Gene (Entity type)
-0.0028797155

Metergoline
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
IL7R
Gene (Entity type)
-0.0033355705

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