Rucaparib (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Rucaparib's neighborhood in the knowledge graph.

Source	Relation	Target	Evidence
N-(6-methoxy-5-(2-methoxyphenoxy)-2-(pyridin-4-yl)pyrimidin-4-yl)-5-methylpyridine-2-sulfonamide Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Rucaparib Compound (Entity type)	0.29328653216362
Rucaparib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ALDH18A1 Gene (Entity type)	0.0040142364
Rucaparib Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Poly [ADP-ribose] polymerase 2 Protein (Entity type)	IC50
Rucaparib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CDKN1A Gene (Entity type)	0.0041271276
Rucaparib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	AQP3 Gene (Entity type)	-0.006500398
Rucaparib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TNFSF10 Gene (Entity type)	-0.0065692295
Rucaparib Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Poly [ADP-ribose] polymerase 1 Protein (Entity type)	IC50
Rucaparib Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Protein mono-ADP-ribosyltransferase PARP3 Protein (Entity type)	IC50
Rucaparib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NOP16 Gene (Entity type)	0.0043107807
Rucaparib Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	SID11114063 Compound (Entity type)	0.5927309989929199

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	Source	Relation	Target	Evidence
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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.