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JNJ-7706621 (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View JNJ-7706621's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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Tools & Use Cases

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	JNJ-7706621 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	GLRX Gene (Entity type)	-0.007836223
	JNJ-7706621 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CHERP Gene (Entity type)	0.009417871
	JNJ-7706621 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CHST15 Gene (Entity type)	0.007716463
	JNJ-7706621 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CDKN3 Gene (Entity type)	-0.007750196
	JNJ-7706621 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	1-(4-Dimethylaminomethyl-phenyl)-8,9-dihydro-7H-2,7,9a-triaza-benzo[cd]azulen-6-one Compound (Entity type)	0.6533080339431763
	JNJ-7706621 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Cyclin-dependent kinase 2 Protein (Entity type)	IC50
	JNJ-7706621 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	AKR1C3 Gene (Entity type)	0.008517432
	JNJ-7706621 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	FASTKD5 Gene (Entity type)	0.009212202
	JNJ-7706621 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TIPARP Gene (Entity type)	0.008307026
	JNJ-7706621 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Aurora kinase A Protein (Entity type)	IC50

JNJ-7706621
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
GLRX
Gene (Entity type)
-0.007836223

JNJ-7706621
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CHERP
Gene (Entity type)
0.009417871

JNJ-7706621
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CHST15
Gene (Entity type)
0.007716463

JNJ-7706621
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CDKN3
Gene (Entity type)
-0.007750196

JNJ-7706621
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
1-(4-Dimethylaminomethyl-phenyl)-8,9-dihydro-7H-2,7,9a-triaza-benzo[cd]azulen-6-one
Compound (Entity type)
0.6533080339431763

JNJ-7706621
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Cyclin-dependent kinase 2
Protein (Entity type)
IC50

JNJ-7706621
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
AKR1C3
Gene (Entity type)
0.008517432

JNJ-7706621
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
FASTKD5
Gene (Entity type)
0.009212202

JNJ-7706621
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TIPARP
Gene (Entity type)
0.008307026

JNJ-7706621
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Aurora kinase A
Protein (Entity type)
IC50

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