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Thapsigargin (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Thapsigargin's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	Thapsigargin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	NMU Gene (Entity type)	-0.0071944455
	Thapsigargin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SLC7A11 Gene (Entity type)	0.014798091
	Thapsigargin Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 Protein (Entity type)	IC50
	Thapsigargin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MTHFD2 Gene (Entity type)	0.012099144
	Thapsigargin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ID2 Gene (Entity type)	-0.0075352574
	Thapsigargin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CHAC1 Gene (Entity type)	0.012660784
	brefeldin-a Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Thapsigargin Compound (Entity type)	0.6566751003265381
	Thapsigargin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HSPA1A Gene (Entity type)	-0.012660551
	Thapsigargin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TRIB3 Gene (Entity type)	0.02196883
	Thapsigargin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CRELD2 Gene (Entity type)	0.01831292

Thapsigargin
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
NMU
Gene (Entity type)
-0.0071944455

Thapsigargin
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SLC7A11
Gene (Entity type)
0.014798091

Thapsigargin
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2
Protein (Entity type)
IC50

Thapsigargin
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MTHFD2
Gene (Entity type)
0.012099144

Thapsigargin
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ID2
Gene (Entity type)
-0.0075352574

Thapsigargin
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CHAC1
Gene (Entity type)
0.012660784

brefeldin-a
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Thapsigargin
Compound (Entity type)
0.6566751003265381

Thapsigargin
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HSPA1A
Gene (Entity type)
-0.012660551

Thapsigargin
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TRIB3
Gene (Entity type)
0.02196883

Thapsigargin
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CRELD2
Gene (Entity type)
0.01831292

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