1-{2-[Bis-(4-trifluoromethyl-phenyl)-methoxy]-ethyl}-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 1-{2-[Bis-(4-trifluoromethyl-phenyl)-methoxy]-ethyl}-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
1-{2-[Bis-(4-trifluoromethyl-phenyl)-methoxy]-ethyl}-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	GJA1 Gene (Entity type)	0.0037285595
Sulfasalazine Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	1-{2-[Bis-(4-trifluoromethyl-phenyl)-methoxy]-ethyl}-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid Compound (Entity type)	0.3290790319442749
1-{2-[Bis-(4-trifluoromethyl-phenyl)-methoxy]-ethyl}-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SLC4A4 Gene (Entity type)	0.0036552646
1-{2-[Bis-(4-trifluoromethyl-phenyl)-methoxy]-ethyl}-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ACKR3 Gene (Entity type)	0.004344881
1-{2-[Bis-(4-trifluoromethyl-phenyl)-methoxy]-ethyl}-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	LSM5 Gene (Entity type)	-0.0039072023
1-{2-[Bis-(4-trifluoromethyl-phenyl)-methoxy]-ethyl}-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PCNA Gene (Entity type)	0.0033239238
1-{2-[Bis-(4-trifluoromethyl-phenyl)-methoxy]-ethyl}-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PEG10 Gene (Entity type)	-0.0037345176
metenkephalin Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	1-{2-[Bis-(4-trifluoromethyl-phenyl)-methoxy]-ethyl}-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid Compound (Entity type)	0.3912736177444458
Nefopam Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	1-{2-[Bis-(4-trifluoromethyl-phenyl)-methoxy]-ethyl}-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid Compound (Entity type)	0.3601387739181518
1-{2-[Bis-(4-trifluoromethyl-phenyl)-methoxy]-ethyl}-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	GPM6B Gene (Entity type)	0.003925819

1-{2-[Bis-(4-trifluoromethyl-phenyl)-methoxy]-ethyl}-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
GJA1
Gene (Entity type)
0.0037285595

Sulfasalazine
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
1-{2-[Bis-(4-trifluoromethyl-phenyl)-methoxy]-ethyl}-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid
Compound (Entity type)
0.3290790319442749

1-{2-[Bis-(4-trifluoromethyl-phenyl)-methoxy]-ethyl}-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SLC4A4
Gene (Entity type)
0.0036552646

1-{2-[Bis-(4-trifluoromethyl-phenyl)-methoxy]-ethyl}-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ACKR3
Gene (Entity type)
0.004344881

1-{2-[Bis-(4-trifluoromethyl-phenyl)-methoxy]-ethyl}-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
LSM5
Gene (Entity type)
-0.0039072023

1-{2-[Bis-(4-trifluoromethyl-phenyl)-methoxy]-ethyl}-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PCNA
Gene (Entity type)
0.0033239238

1-{2-[Bis-(4-trifluoromethyl-phenyl)-methoxy]-ethyl}-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PEG10
Gene (Entity type)
-0.0037345176

metenkephalin
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
1-{2-[Bis-(4-trifluoromethyl-phenyl)-methoxy]-ethyl}-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid
Compound (Entity type)
0.3912736177444458

Nefopam
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
1-{2-[Bis-(4-trifluoromethyl-phenyl)-methoxy]-ethyl}-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid
Compound (Entity type)
0.3601387739181518

1-{2-[Bis-(4-trifluoromethyl-phenyl)-methoxy]-ethyl}-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
GPM6B
Gene (Entity type)
0.003925819

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