[6-Hydroxy-2-(4-hydroxy-phenyl)-benzo[b]thiophen-3-yl]-[4-(4-isopropyl-piperazin-1-yl)-phenyl]-methanone (Compound)

Description: A compound in the knowledge graph

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View [6-Hydroxy-2-(4-hydroxy-phenyl)-benzo[b]thiophen-3-yl]-[4-(4-isopropyl-piperazin-1-yl)-phenyl]-methanone's neighborhood in the knowledge graph.

Submit

Knowledge Graph Assertions

Source	Relation	Target	Evidence
[6-Hydroxy-2-(4-hydroxy-phenyl)-benzo[b]thiophen-3-yl]-[4-(4-isopropyl-piperazin-1-yl)-phenyl]-methanone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	S100A8 Gene (Entity type)	-0.011459045
[6-Hydroxy-2-(4-hydroxy-phenyl)-benzo[b]thiophen-3-yl]-[4-(4-isopropyl-piperazin-1-yl)-phenyl]-methanone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ACAT2 Gene (Entity type)	0.01279075
[6-Hydroxy-2-(4-hydroxy-phenyl)-benzo[b]thiophen-3-yl]-[4-(4-isopropyl-piperazin-1-yl)-phenyl]-methanone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CYP51A1 Gene (Entity type)	0.016734734
[6-Hydroxy-2-(4-hydroxy-phenyl)-benzo[b]thiophen-3-yl]-[4-(4-isopropyl-piperazin-1-yl)-phenyl]-methanone Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	terfenadine Compound (Entity type)	0.5842692255973816
[6-Hydroxy-2-(4-hydroxy-phenyl)-benzo[b]thiophen-3-yl]-[4-(4-isopropyl-piperazin-1-yl)-phenyl]-methanone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	KRT17 Gene (Entity type)	-0.011931408
[6-Hydroxy-2-(4-hydroxy-phenyl)-benzo[b]thiophen-3-yl]-[4-(4-isopropyl-piperazin-1-yl)-phenyl]-methanone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	INSIG1 Gene (Entity type)	0.027957803
[6-Hydroxy-2-(4-hydroxy-phenyl)-benzo[b]thiophen-3-yl]-[4-(4-isopropyl-piperazin-1-yl)-phenyl]-methanone Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	SID11113832 Compound (Entity type)	0.5995840430259705
[6-Hydroxy-2-(4-hydroxy-phenyl)-benzo[b]thiophen-3-yl]-[4-(4-isopropyl-piperazin-1-yl)-phenyl]-methanone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	RPP40 Gene (Entity type)	-0.010288106
[6-Hydroxy-2-(4-hydroxy-phenyl)-benzo[b]thiophen-3-yl]-[4-(4-isopropyl-piperazin-1-yl)-phenyl]-methanone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ARMCX1 Gene (Entity type)	0.014307444
[6-Hydroxy-2-(4-hydroxy-phenyl)-benzo[b]thiophen-3-yl]-[4-(4-isopropyl-piperazin-1-yl)-phenyl]-methanone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HMOX1 Gene (Entity type)	0.014581215

[6-Hydroxy-2-(4-hydroxy-phenyl)-benzo[b]thiophen-3-yl]-[4-(4-isopropyl-piperazin-1-yl)-phenyl]-methanone
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
S100A8
Gene (Entity type)
-0.011459045

[6-Hydroxy-2-(4-hydroxy-phenyl)-benzo[b]thiophen-3-yl]-[4-(4-isopropyl-piperazin-1-yl)-phenyl]-methanone
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ACAT2
Gene (Entity type)
0.01279075

[6-Hydroxy-2-(4-hydroxy-phenyl)-benzo[b]thiophen-3-yl]-[4-(4-isopropyl-piperazin-1-yl)-phenyl]-methanone
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CYP51A1
Gene (Entity type)
0.016734734

[6-Hydroxy-2-(4-hydroxy-phenyl)-benzo[b]thiophen-3-yl]-[4-(4-isopropyl-piperazin-1-yl)-phenyl]-methanone
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
terfenadine
Compound (Entity type)
0.5842692255973816

[6-Hydroxy-2-(4-hydroxy-phenyl)-benzo[b]thiophen-3-yl]-[4-(4-isopropyl-piperazin-1-yl)-phenyl]-methanone
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
KRT17
Gene (Entity type)
-0.011931408

[6-Hydroxy-2-(4-hydroxy-phenyl)-benzo[b]thiophen-3-yl]-[4-(4-isopropyl-piperazin-1-yl)-phenyl]-methanone
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
INSIG1
Gene (Entity type)
0.027957803

[6-Hydroxy-2-(4-hydroxy-phenyl)-benzo[b]thiophen-3-yl]-[4-(4-isopropyl-piperazin-1-yl)-phenyl]-methanone
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
SID11113832
Compound (Entity type)
0.5995840430259705

[6-Hydroxy-2-(4-hydroxy-phenyl)-benzo[b]thiophen-3-yl]-[4-(4-isopropyl-piperazin-1-yl)-phenyl]-methanone
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
RPP40
Gene (Entity type)
-0.010288106

[6-Hydroxy-2-(4-hydroxy-phenyl)-benzo[b]thiophen-3-yl]-[4-(4-isopropyl-piperazin-1-yl)-phenyl]-methanone
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ARMCX1
Gene (Entity type)
0.014307444

[6-Hydroxy-2-(4-hydroxy-phenyl)-benzo[b]thiophen-3-yl]-[4-(4-isopropyl-piperazin-1-yl)-phenyl]-methanone
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
HMOX1
Gene (Entity type)
0.014581215

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