(8S,9R,12S)-12-(1H-Indole-3-carbonyl)-9-isobutyl-10-oxo-2-oxa-11-aza-bicyclo[12.2.2]octadeca-1(17),14(18),15-triene-8-carboxylic acid hydroxyamide (Compound)

Description: A compound in the knowledge graph

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View (8S,9R,12S)-12-(1H-Indole-3-carbonyl)-9-isobutyl-10-oxo-2-oxa-11-aza-bicyclo[12.2.2]octadeca-1(17),14(18),15-triene-8-carboxylic acid hydroxyamide's neighborhood in the knowledge graph.

Submit

Knowledge Graph Assertions

Source	Relation	Target	Evidence
(8S,9R,12S)-12-(1H-Indole-3-carbonyl)-9-isobutyl-10-oxo-2-oxa-11-aza-bicyclo[12.2.2]octadeca-1(17),14(18),15-triene-8-carboxylic acid hydroxyamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	72 kDa type IV collagenase Protein (Entity type)	IC50
(8S,9R,12S)-12-(1H-Indole-3-carbonyl)-9-isobutyl-10-oxo-2-oxa-11-aza-bicyclo[12.2.2]octadeca-1(17),14(18),15-triene-8-carboxylic acid hydroxyamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Stromelysin-1 Protein (Entity type)	IC50
(8S,9R,12S)-12-(1H-Indole-3-carbonyl)-9-isobutyl-10-oxo-2-oxa-11-aza-bicyclo[12.2.2]octadeca-1(17),14(18),15-triene-8-carboxylic acid hydroxyamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Interstitial collagenase Protein (Entity type)	IC50
(8S,9R,12S)-12-(1H-Indole-3-carbonyl)-9-isobutyl-10-oxo-2-oxa-11-aza-bicyclo[12.2.2]octadeca-1(17),14(18),15-triene-8-carboxylic acid hydroxyamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Matrilysin Protein (Entity type)	IC50

(8S,9R,12S)-12-(1H-Indole-3-carbonyl)-9-isobutyl-10-oxo-2-oxa-11-aza-bicyclo[12.2.2]octadeca-1(17),14(18),15-triene-8-carboxylic acid hydroxyamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
72 kDa type IV collagenase
Protein (Entity type)
IC50

(8S,9R,12S)-12-(1H-Indole-3-carbonyl)-9-isobutyl-10-oxo-2-oxa-11-aza-bicyclo[12.2.2]octadeca-1(17),14(18),15-triene-8-carboxylic acid hydroxyamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Stromelysin-1
Protein (Entity type)
IC50

(8S,9R,12S)-12-(1H-Indole-3-carbonyl)-9-isobutyl-10-oxo-2-oxa-11-aza-bicyclo[12.2.2]octadeca-1(17),14(18),15-triene-8-carboxylic acid hydroxyamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Interstitial collagenase
Protein (Entity type)
IC50

(8S,9R,12S)-12-(1H-Indole-3-carbonyl)-9-isobutyl-10-oxo-2-oxa-11-aza-bicyclo[12.2.2]octadeca-1(17),14(18),15-triene-8-carboxylic acid hydroxyamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Matrilysin
Protein (Entity type)
IC50

DISPLAY PER PAGE

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
Loading results...

DISPLAY PER PAGE

CFDE Workbench

Consortium

Community

Resources

@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.