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lacosamide (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View lacosamide's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	lacosamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SPINK1 Gene (Entity type)	0.0056955847
	lacosamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ADH5 Gene (Entity type)	0.004748718
	lacosamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	QPCT Gene (Entity type)	-0.0051490474
	lacosamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PRDX2 Gene (Entity type)	0.004734554
	lacosamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	AQP3 Gene (Entity type)	0.005517768
	Entecavir Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	lacosamide Compound (Entity type)	0.4494962692260742
	lacosamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Carbonic anhydrase 5B, mitochondrial Protein (Entity type)	Ki
	lacosamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	RHOB Gene (Entity type)	-0.0048153196
	2-methoxy-N-(3-(4-(3-methyl-4-(6-methylpyridin-3-yloxy)phenylamino)quinazolin-6-yl)allyl)acetamide Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	lacosamide Compound (Entity type)	0.3296786844730377
	lacosamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	H1-0 Gene (Entity type)	-0.005296117

lacosamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SPINK1
Gene (Entity type)
0.0056955847

lacosamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ADH5
Gene (Entity type)
0.004748718

lacosamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
QPCT
Gene (Entity type)
-0.0051490474

lacosamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PRDX2
Gene (Entity type)
0.004734554

lacosamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
AQP3
Gene (Entity type)
0.005517768

Entecavir
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
lacosamide
Compound (Entity type)
0.4494962692260742

lacosamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Carbonic anhydrase 5B, mitochondrial
Protein (Entity type)
Ki

lacosamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
RHOB
Gene (Entity type)
-0.0048153196

2-methoxy-N-(3-(4-(3-methyl-4-(6-methylpyridin-3-yloxy)phenylamino)quinazolin-6-yl)allyl)acetamide
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
lacosamide
Compound (Entity type)
0.3296786844730377

lacosamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
H1-0
Gene (Entity type)
-0.005296117

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