N-((2S,3S)-4-(4-chlorophenyl)-3-(3-cyanophenyl)butan-2-yl)-2-methyl-2-(5-(trifluoromethyl)pyridin-2-yloxy)propanamide (Compound)

Description: A compound in the knowledge graph

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View N-((2S,3S)-4-(4-chlorophenyl)-3-(3-cyanophenyl)butan-2-yl)-2-methyl-2-(5-(trifluoromethyl)pyridin-2-yloxy)propanamide's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
N-((2S,3S)-4-(4-chlorophenyl)-3-(3-cyanophenyl)butan-2-yl)-2-methyl-2-(5-(trifluoromethyl)pyridin-2-yloxy)propanamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PLOD2 Gene (Entity type)	-0.0058986163
Lersivirine Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	N-((2S,3S)-4-(4-chlorophenyl)-3-(3-cyanophenyl)butan-2-yl)-2-methyl-2-(5-(trifluoromethyl)pyridin-2-yloxy)propanamide Compound (Entity type)	0.4858745634555816
N-((2S,3S)-4-(4-chlorophenyl)-3-(3-cyanophenyl)butan-2-yl)-2-methyl-2-(5-(trifluoromethyl)pyridin-2-yloxy)propanamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	AMIGO2 Gene (Entity type)	0.011494457
N-((2S,3S)-4-(4-chlorophenyl)-3-(3-cyanophenyl)butan-2-yl)-2-methyl-2-(5-(trifluoromethyl)pyridin-2-yloxy)propanamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CEP15 Gene (Entity type)	0.005601067
N-((2S,3S)-4-(4-chlorophenyl)-3-(3-cyanophenyl)butan-2-yl)-2-methyl-2-(5-(trifluoromethyl)pyridin-2-yloxy)propanamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TRIB2 Gene (Entity type)	-0.005916423
N-((2S,3S)-4-(4-chlorophenyl)-3-(3-cyanophenyl)butan-2-yl)-2-methyl-2-(5-(trifluoromethyl)pyridin-2-yloxy)propanamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TUBB2A Gene (Entity type)	-0.009106377
N-((2S,3S)-4-(4-chlorophenyl)-3-(3-cyanophenyl)butan-2-yl)-2-methyl-2-(5-(trifluoromethyl)pyridin-2-yloxy)propanamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MBP Gene (Entity type)	0.0055001983
N-((2S,3S)-4-(4-chlorophenyl)-3-(3-cyanophenyl)butan-2-yl)-2-methyl-2-(5-(trifluoromethyl)pyridin-2-yloxy)propanamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	LY6E Gene (Entity type)	0.0069065145
N-((2S,3S)-4-(4-chlorophenyl)-3-(3-cyanophenyl)butan-2-yl)-2-methyl-2-(5-(trifluoromethyl)pyridin-2-yloxy)propanamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IGFBP4 Gene (Entity type)	0.0050659734
N-((2S,3S)-4-(4-chlorophenyl)-3-(3-cyanophenyl)butan-2-yl)-2-methyl-2-(5-(trifluoromethyl)pyridin-2-yloxy)propanamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MT1H Gene (Entity type)	-0.0056980993

N-((2S,3S)-4-(4-chlorophenyl)-3-(3-cyanophenyl)butan-2-yl)-2-methyl-2-(5-(trifluoromethyl)pyridin-2-yloxy)propanamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PLOD2
Gene (Entity type)
-0.0058986163

Lersivirine
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
N-((2S,3S)-4-(4-chlorophenyl)-3-(3-cyanophenyl)butan-2-yl)-2-methyl-2-(5-(trifluoromethyl)pyridin-2-yloxy)propanamide
Compound (Entity type)
0.4858745634555816

N-((2S,3S)-4-(4-chlorophenyl)-3-(3-cyanophenyl)butan-2-yl)-2-methyl-2-(5-(trifluoromethyl)pyridin-2-yloxy)propanamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
AMIGO2
Gene (Entity type)
0.011494457

N-((2S,3S)-4-(4-chlorophenyl)-3-(3-cyanophenyl)butan-2-yl)-2-methyl-2-(5-(trifluoromethyl)pyridin-2-yloxy)propanamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CEP15
Gene (Entity type)
0.005601067

N-((2S,3S)-4-(4-chlorophenyl)-3-(3-cyanophenyl)butan-2-yl)-2-methyl-2-(5-(trifluoromethyl)pyridin-2-yloxy)propanamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TRIB2
Gene (Entity type)
-0.005916423

N-((2S,3S)-4-(4-chlorophenyl)-3-(3-cyanophenyl)butan-2-yl)-2-methyl-2-(5-(trifluoromethyl)pyridin-2-yloxy)propanamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TUBB2A
Gene (Entity type)
-0.009106377

N-((2S,3S)-4-(4-chlorophenyl)-3-(3-cyanophenyl)butan-2-yl)-2-methyl-2-(5-(trifluoromethyl)pyridin-2-yloxy)propanamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MBP
Gene (Entity type)
0.0055001983

N-((2S,3S)-4-(4-chlorophenyl)-3-(3-cyanophenyl)butan-2-yl)-2-methyl-2-(5-(trifluoromethyl)pyridin-2-yloxy)propanamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
LY6E
Gene (Entity type)
0.0069065145

N-((2S,3S)-4-(4-chlorophenyl)-3-(3-cyanophenyl)butan-2-yl)-2-methyl-2-(5-(trifluoromethyl)pyridin-2-yloxy)propanamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
IGFBP4
Gene (Entity type)
0.0050659734

N-((2S,3S)-4-(4-chlorophenyl)-3-(3-cyanophenyl)butan-2-yl)-2-methyl-2-(5-(trifluoromethyl)pyridin-2-yloxy)propanamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MT1H
Gene (Entity type)
-0.0056980993

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Knowledge Graph Assertions

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