(3R)-2'-(4-bromo-2-fluorobenzyl)-1'H,2H,5H-spiro[pyrrolidine-3,4'-pyrrolo[1,2-a]pyrazine]-1',2,3',5(2'H)-tetrone (Compound)

Description: A compound in the knowledge graph

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View (3R)-2'-(4-bromo-2-fluorobenzyl)-1'H,2H,5H-spiro[pyrrolidine-3,4'-pyrrolo[1,2-a]pyrazine]-1',2,3',5(2'H)-tetrone's neighborhood in the knowledge graph.

Submit

Knowledge Graph Assertions

Source	Relation	Target	Evidence
(3R)-2'-(4-bromo-2-fluorobenzyl)-1'H,2H,5H-spiro[pyrrolidine-3,4'-pyrrolo[1,2-a]pyrazine]-1',2,3',5(2'H)-tetrone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TRPM4 Gene (Entity type)	-0.0043794583
(3R)-2'-(4-bromo-2-fluorobenzyl)-1'H,2H,5H-spiro[pyrrolidine-3,4'-pyrrolo[1,2-a]pyrazine]-1',2,3',5(2'H)-tetrone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	NVL Gene (Entity type)	-0.0052241813
(3R)-2'-(4-bromo-2-fluorobenzyl)-1'H,2H,5H-spiro[pyrrolidine-3,4'-pyrrolo[1,2-a]pyrazine]-1',2,3',5(2'H)-tetrone Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Montelukast Compound (Entity type)	0.1337231248617172
(3R)-2'-(4-bromo-2-fluorobenzyl)-1'H,2H,5H-spiro[pyrrolidine-3,4'-pyrrolo[1,2-a]pyrazine]-1',2,3',5(2'H)-tetrone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MXRA7 Gene (Entity type)	-0.004594006
(3R)-2'-(4-bromo-2-fluorobenzyl)-1'H,2H,5H-spiro[pyrrolidine-3,4'-pyrrolo[1,2-a]pyrazine]-1',2,3',5(2'H)-tetrone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TTN Gene (Entity type)	0.0053452873
(3R)-2'-(4-bromo-2-fluorobenzyl)-1'H,2H,5H-spiro[pyrrolidine-3,4'-pyrrolo[1,2-a]pyrazine]-1',2,3',5(2'H)-tetrone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ZNF395 Gene (Entity type)	-0.008580612
(3R)-2'-(4-bromo-2-fluorobenzyl)-1'H,2H,5H-spiro[pyrrolidine-3,4'-pyrrolo[1,2-a]pyrazine]-1',2,3',5(2'H)-tetrone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TARBP1 Gene (Entity type)	0.0060177124
(3R)-2'-(4-bromo-2-fluorobenzyl)-1'H,2H,5H-spiro[pyrrolidine-3,4'-pyrrolo[1,2-a]pyrazine]-1',2,3',5(2'H)-tetrone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PGAM1 Gene (Entity type)	-0.0060338425
(3R)-2'-(4-bromo-2-fluorobenzyl)-1'H,2H,5H-spiro[pyrrolidine-3,4'-pyrrolo[1,2-a]pyrazine]-1',2,3',5(2'H)-tetrone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	FABP1 Gene (Entity type)	0.0057087387
(3R)-2'-(4-bromo-2-fluorobenzyl)-1'H,2H,5H-spiro[pyrrolidine-3,4'-pyrrolo[1,2-a]pyrazine]-1',2,3',5(2'H)-tetrone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	WASHC4 Gene (Entity type)	-0.005435615