6-chloro-9-((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)-9H-purin-2-amine (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 6-chloro-9-((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)-9H-purin-2-amine's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
6-chloro-9-((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)-9H-purin-2-amine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DNAJA1 Gene (Entity type)	0.011504431
6-chloro-9-((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)-9H-purin-2-amine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	FXR1 Gene (Entity type)	0.013091374
4-[4-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-5-methyl-1H-pyrazol-3-yl]-6-ethyl-benzene-1,3-diol Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	6-chloro-9-((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)-9H-purin-2-amine Compound (Entity type)	0.5835047960281372
6-chloro-9-((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)-9H-purin-2-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MMP1 Gene (Entity type)	-0.012240941
6-chloro-9-((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)-9H-purin-2-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	GREM1 Gene (Entity type)	-0.011776931
6-chloro-9-((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)-9H-purin-2-amine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HSPH1 Gene (Entity type)	0.018923534
6-chloro-9-((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)-9H-purin-2-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SNAI2 Gene (Entity type)	-0.012987307
6-chloro-9-((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)-9H-purin-2-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PHLDA1 Gene (Entity type)	-0.016815681
6-chloro-9-((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)-9H-purin-2-amine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HSPB1 Gene (Entity type)	0.0143612465
6-chloro-9-((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)-9H-purin-2-amine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DNAJB1 Gene (Entity type)	0.012101935

6-chloro-9-((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)-9H-purin-2-amine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
DNAJA1
Gene (Entity type)
0.011504431

6-chloro-9-((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)-9H-purin-2-amine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
FXR1
Gene (Entity type)
0.013091374

4-[4-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-5-methyl-1H-pyrazol-3-yl]-6-ethyl-benzene-1,3-diol
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
6-chloro-9-((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)-9H-purin-2-amine
Compound (Entity type)
0.5835047960281372

6-chloro-9-((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)-9H-purin-2-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MMP1
Gene (Entity type)
-0.012240941

6-chloro-9-((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)-9H-purin-2-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
GREM1
Gene (Entity type)
-0.011776931

6-chloro-9-((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)-9H-purin-2-amine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
HSPH1
Gene (Entity type)
0.018923534

6-chloro-9-((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)-9H-purin-2-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SNAI2
Gene (Entity type)
-0.012987307

6-chloro-9-((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)-9H-purin-2-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PHLDA1
Gene (Entity type)
-0.016815681

6-chloro-9-((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)-9H-purin-2-amine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
HSPB1
Gene (Entity type)
0.0143612465

6-chloro-9-((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)-9H-purin-2-amine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
DNAJB1
Gene (Entity type)
0.012101935

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