1-tert-butyl-3-(naphthalen-1-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 1-tert-butyl-3-(naphthalen-1-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
1-tert-butyl-3-(naphthalen-1-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	AQP3 Gene (Entity type)	0.017957035
1-tert-butyl-3-(naphthalen-1-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ADA Gene (Entity type)	0.012076018
1-tert-butyl-3-(naphthalen-1-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	KDM5D Gene (Entity type)	0.0124486815
1-tert-butyl-3-(naphthalen-1-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	BGN Gene (Entity type)	-0.012626927
1-tert-butyl-3-(naphthalen-1-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	THBS4 Gene (Entity type)	-0.013440213
1-tert-butyl-3-(naphthalen-1-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HSPA6 Gene (Entity type)	-0.013182907
1-tert-butyl-3-(naphthalen-1-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	FKBP11 Gene (Entity type)	0.012487703
1-tert-butyl-3-(naphthalen-1-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	FLOT1 Gene (Entity type)	0.012193346
1-tert-butyl-3-(naphthalen-1-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IGFBP2 Gene (Entity type)	0.01625617
1-tert-butyl-3-(naphthalen-1-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SERPINA3 Gene (Entity type)	-0.013343753

1-tert-butyl-3-(naphthalen-1-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
AQP3
Gene (Entity type)
0.017957035

1-tert-butyl-3-(naphthalen-1-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ADA
Gene (Entity type)
0.012076018

1-tert-butyl-3-(naphthalen-1-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
KDM5D
Gene (Entity type)
0.0124486815

1-tert-butyl-3-(naphthalen-1-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
BGN
Gene (Entity type)
-0.012626927

1-tert-butyl-3-(naphthalen-1-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
THBS4
Gene (Entity type)
-0.013440213

1-tert-butyl-3-(naphthalen-1-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HSPA6
Gene (Entity type)
-0.013182907

1-tert-butyl-3-(naphthalen-1-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
FKBP11
Gene (Entity type)
0.012487703

1-tert-butyl-3-(naphthalen-1-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
FLOT1
Gene (Entity type)
0.012193346

1-tert-butyl-3-(naphthalen-1-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
IGFBP2
Gene (Entity type)
0.01625617

1-tert-butyl-3-(naphthalen-1-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SERPINA3
Gene (Entity type)
-0.013343753

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