(5-(2-((2R,6S)-2,6-dimethylmorpholino)-4-morpholinopyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View (5-(2-((2R,6S)-2,6-dimethylmorpholino)-4-morpholinopyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
(5-(2-((2R,6S)-2,6-dimethylmorpholino)-4-morpholinopyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	F2RL1 Gene (Entity type)	0.011412454
(5-(2-((2R,6S)-2,6-dimethylmorpholino)-4-morpholinopyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CCN2 Gene (Entity type)	0.017119432
5-(9-isopropyl-8-methyl-2-morpholino-9H-purin-6-yl)pyrimidin-2-amine Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	(5-(2-((2R,6S)-2,6-dimethylmorpholino)-4-morpholinopyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol Compound (Entity type)	0.708084762096405
1-(4-(4-Propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2(1H)-one Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	(5-(2-((2R,6S)-2,6-dimethylmorpholino)-4-morpholinopyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol Compound (Entity type)	0.8209730386734009
(5-(2-((2R,6S)-2,6-dimethylmorpholino)-4-morpholinopyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PHGDH Gene (Entity type)	-0.018758155
Methyl 4-(6-{4-[(methoxycarbonyl)amino]phenyl}-4-morpholin-4-yl-1Hpyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	(5-(2-((2R,6S)-2,6-dimethylmorpholino)-4-morpholinopyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol Compound (Entity type)	0.775840163230896
(5-(2-((2R,6S)-2,6-dimethylmorpholino)-4-morpholinopyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DUSP6 Gene (Entity type)	0.019644443
(5-(2-((2R,6S)-2,6-dimethylmorpholino)-4-morpholinopyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SLC7A5 Gene (Entity type)	-0.013291981
(5-(2-((2R,6S)-2,6-dimethylmorpholino)-4-morpholinopyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NOP53 Gene (Entity type)	0.013455408
(5-(2-((2R,6S)-2,6-dimethylmorpholino)-4-morpholinopyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	dactolisib Compound (Entity type)	0.9168373346328736

(5-(2-((2R,6S)-2,6-dimethylmorpholino)-4-morpholinopyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
F2RL1
Gene (Entity type)
0.011412454

(5-(2-((2R,6S)-2,6-dimethylmorpholino)-4-morpholinopyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CCN2
Gene (Entity type)
0.017119432

5-(9-isopropyl-8-methyl-2-morpholino-9H-purin-6-yl)pyrimidin-2-amine
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
(5-(2-((2R,6S)-2,6-dimethylmorpholino)-4-morpholinopyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol
Compound (Entity type)
0.708084762096405

1-(4-(4-Propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2(1H)-one
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
(5-(2-((2R,6S)-2,6-dimethylmorpholino)-4-morpholinopyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol
Compound (Entity type)
0.8209730386734009

(5-(2-((2R,6S)-2,6-dimethylmorpholino)-4-morpholinopyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PHGDH
Gene (Entity type)
-0.018758155

Methyl 4-(6-{4-[(methoxycarbonyl)amino]phenyl}-4-morpholin-4-yl-1Hpyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
(5-(2-((2R,6S)-2,6-dimethylmorpholino)-4-morpholinopyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol
Compound (Entity type)
0.775840163230896

(5-(2-((2R,6S)-2,6-dimethylmorpholino)-4-morpholinopyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
DUSP6
Gene (Entity type)
0.019644443

(5-(2-((2R,6S)-2,6-dimethylmorpholino)-4-morpholinopyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SLC7A5
Gene (Entity type)
-0.013291981

(5-(2-((2R,6S)-2,6-dimethylmorpholino)-4-morpholinopyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
NOP53
Gene (Entity type)
0.013455408

(5-(2-((2R,6S)-2,6-dimethylmorpholino)-4-morpholinopyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
dactolisib
Compound (Entity type)
0.9168373346328736

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