4-(8-Methyl-9H-1,3-dioxa-6,7-diaza-cyclohepta[f]inden-5-yl)-phenylamine (Compound)

Description: A compound in the knowledge graph

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 4-(8-Methyl-9H-1,3-dioxa-6,7-diaza-cyclohepta[f]inden-5-yl)-phenylamine's neighborhood in the knowledge graph.

Submit

Knowledge Graph Assertions

Source	Relation	Target	Evidence
4-(8-Methyl-9H-1,3-dioxa-6,7-diaza-cyclohepta[f]inden-5-yl)-phenylamine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	VSIG4 Gene (Entity type)	0.007987423
4-(8-Methyl-9H-1,3-dioxa-6,7-diaza-cyclohepta[f]inden-5-yl)-phenylamine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NGRN Gene (Entity type)	0.0077997344
4-(8-Methyl-9H-1,3-dioxa-6,7-diaza-cyclohepta[f]inden-5-yl)-phenylamine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MYH10 Gene (Entity type)	0.008217334
4-(8-Methyl-9H-1,3-dioxa-6,7-diaza-cyclohepta[f]inden-5-yl)-phenylamine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PAK1 Gene (Entity type)	-0.009095088
4-(8-Methyl-9H-1,3-dioxa-6,7-diaza-cyclohepta[f]inden-5-yl)-phenylamine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SPRR3 Gene (Entity type)	0.009177593
4-(8-Methyl-9H-1,3-dioxa-6,7-diaza-cyclohepta[f]inden-5-yl)-phenylamine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	F2RL1 Gene (Entity type)	-0.0080503505
4-(8-Methyl-9H-1,3-dioxa-6,7-diaza-cyclohepta[f]inden-5-yl)-phenylamine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	FOXG1 Gene (Entity type)	0.007595355
4-(8-Methyl-9H-1,3-dioxa-6,7-diaza-cyclohepta[f]inden-5-yl)-phenylamine Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Roflumilast Compound (Entity type)	0.2740573585033417
4-(8-Methyl-9H-1,3-dioxa-6,7-diaza-cyclohepta[f]inden-5-yl)-phenylamine Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Thalidomide Compound (Entity type)	0.2716162204742431
4-(8-Methyl-9H-1,3-dioxa-6,7-diaza-cyclohepta[f]inden-5-yl)-phenylamine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SLC7A11 Gene (Entity type)	-0.008262795

4-(8-Methyl-9H-1,3-dioxa-6,7-diaza-cyclohepta[f]inden-5-yl)-phenylamine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
VSIG4
Gene (Entity type)
0.007987423

4-(8-Methyl-9H-1,3-dioxa-6,7-diaza-cyclohepta[f]inden-5-yl)-phenylamine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
NGRN
Gene (Entity type)
0.0077997344

4-(8-Methyl-9H-1,3-dioxa-6,7-diaza-cyclohepta[f]inden-5-yl)-phenylamine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MYH10
Gene (Entity type)
0.008217334

4-(8-Methyl-9H-1,3-dioxa-6,7-diaza-cyclohepta[f]inden-5-yl)-phenylamine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PAK1
Gene (Entity type)
-0.009095088

4-(8-Methyl-9H-1,3-dioxa-6,7-diaza-cyclohepta[f]inden-5-yl)-phenylamine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SPRR3
Gene (Entity type)
0.009177593

4-(8-Methyl-9H-1,3-dioxa-6,7-diaza-cyclohepta[f]inden-5-yl)-phenylamine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
F2RL1
Gene (Entity type)
-0.0080503505

4-(8-Methyl-9H-1,3-dioxa-6,7-diaza-cyclohepta[f]inden-5-yl)-phenylamine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
FOXG1
Gene (Entity type)
0.007595355

4-(8-Methyl-9H-1,3-dioxa-6,7-diaza-cyclohepta[f]inden-5-yl)-phenylamine
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Roflumilast
Compound (Entity type)
0.2740573585033417

4-(8-Methyl-9H-1,3-dioxa-6,7-diaza-cyclohepta[f]inden-5-yl)-phenylamine
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Thalidomide
Compound (Entity type)
0.2716162204742431

4-(8-Methyl-9H-1,3-dioxa-6,7-diaza-cyclohepta[f]inden-5-yl)-phenylamine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SLC7A11
Gene (Entity type)
-0.008262795

DISPLAY PER PAGE

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
Loading results...

DISPLAY PER PAGE

CFDE Workbench

Consortium

Community

Resources

@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.