[1-(4-Fluoro-benzyl)-1H-benzoimidazol-2-yl]-{1-[2-(4-methoxy-phenyl)-ethyl]-piperidin-4-yl}-amine (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View [1-(4-Fluoro-benzyl)-1H-benzoimidazol-2-yl]-{1-[2-(4-methoxy-phenyl)-ethyl]-piperidin-4-yl}-amine's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
[1-(4-Fluoro-benzyl)-1H-benzoimidazol-2-yl]-{1-[2-(4-methoxy-phenyl)-ethyl]-piperidin-4-yl}-amine Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Potassium voltage-gated channel subfamily H member 2 Protein (Entity type)	IC50
[1-(4-Fluoro-benzyl)-1H-benzoimidazol-2-yl]-{1-[2-(4-methoxy-phenyl)-ethyl]-piperidin-4-yl}-amine Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	ATP-dependent translocase ABCB1 Protein (Entity type)	IC50
[1-(4-Fluoro-benzyl)-1H-benzoimidazol-2-yl]-{1-[2-(4-methoxy-phenyl)-ethyl]-piperidin-4-yl}-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PPP1R14B Gene (Entity type)	-0.016360793
[1-(4-Fluoro-benzyl)-1H-benzoimidazol-2-yl]-{1-[2-(4-methoxy-phenyl)-ethyl]-piperidin-4-yl}-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SUPV3L1 Gene (Entity type)	-0.024645323
[1-(4-Fluoro-benzyl)-1H-benzoimidazol-2-yl]-{1-[2-(4-methoxy-phenyl)-ethyl]-piperidin-4-yl}-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	EIF2S3 Gene (Entity type)	-0.019067908
[1-(4-Fluoro-benzyl)-1H-benzoimidazol-2-yl]-{1-[2-(4-methoxy-phenyl)-ethyl]-piperidin-4-yl}-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	RRS1 Gene (Entity type)	-0.019218044
[1-(4-Fluoro-benzyl)-1H-benzoimidazol-2-yl]-{1-[2-(4-methoxy-phenyl)-ethyl]-piperidin-4-yl}-amine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SC5D Gene (Entity type)	0.018341426
[1-(4-Fluoro-benzyl)-1H-benzoimidazol-2-yl]-{1-[2-(4-methoxy-phenyl)-ethyl]-piperidin-4-yl}-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CNN3 Gene (Entity type)	-0.020502398
[1-(4-Fluoro-benzyl)-1H-benzoimidazol-2-yl]-{1-[2-(4-methoxy-phenyl)-ethyl]-piperidin-4-yl}-amine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MSMO1 Gene (Entity type)	0.017349143
[1-(4-Fluoro-benzyl)-1H-benzoimidazol-2-yl]-{1-[2-(4-methoxy-phenyl)-ethyl]-piperidin-4-yl}-amine Compound (Entity type)	Indication Knowledge Graph Relation (Entity type)	Allergic Conjunctivitis Disease or Phenotype (Entity type)

[1-(4-Fluoro-benzyl)-1H-benzoimidazol-2-yl]-{1-[2-(4-methoxy-phenyl)-ethyl]-piperidin-4-yl}-amine
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Potassium voltage-gated channel subfamily H member 2
Protein (Entity type)
IC50

[1-(4-Fluoro-benzyl)-1H-benzoimidazol-2-yl]-{1-[2-(4-methoxy-phenyl)-ethyl]-piperidin-4-yl}-amine
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
ATP-dependent translocase ABCB1
Protein (Entity type)
IC50

[1-(4-Fluoro-benzyl)-1H-benzoimidazol-2-yl]-{1-[2-(4-methoxy-phenyl)-ethyl]-piperidin-4-yl}-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PPP1R14B
Gene (Entity type)
-0.016360793

[1-(4-Fluoro-benzyl)-1H-benzoimidazol-2-yl]-{1-[2-(4-methoxy-phenyl)-ethyl]-piperidin-4-yl}-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SUPV3L1
Gene (Entity type)
-0.024645323

[1-(4-Fluoro-benzyl)-1H-benzoimidazol-2-yl]-{1-[2-(4-methoxy-phenyl)-ethyl]-piperidin-4-yl}-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
EIF2S3
Gene (Entity type)
-0.019067908

[1-(4-Fluoro-benzyl)-1H-benzoimidazol-2-yl]-{1-[2-(4-methoxy-phenyl)-ethyl]-piperidin-4-yl}-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
RRS1
Gene (Entity type)
-0.019218044

[1-(4-Fluoro-benzyl)-1H-benzoimidazol-2-yl]-{1-[2-(4-methoxy-phenyl)-ethyl]-piperidin-4-yl}-amine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SC5D
Gene (Entity type)
0.018341426

[1-(4-Fluoro-benzyl)-1H-benzoimidazol-2-yl]-{1-[2-(4-methoxy-phenyl)-ethyl]-piperidin-4-yl}-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CNN3
Gene (Entity type)
-0.020502398

[1-(4-Fluoro-benzyl)-1H-benzoimidazol-2-yl]-{1-[2-(4-methoxy-phenyl)-ethyl]-piperidin-4-yl}-amine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MSMO1
Gene (Entity type)
0.017349143

[1-(4-Fluoro-benzyl)-1H-benzoimidazol-2-yl]-{1-[2-(4-methoxy-phenyl)-ethyl]-piperidin-4-yl}-amine
Compound (Entity type)
Indication
Knowledge Graph Relation (Entity type)
Allergic Conjunctivitis
Disease or Phenotype (Entity type)

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Knowledge Graph Assertions

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