5-(3-tert-Butylamino-2-hydroxy-propoxy)-3,4-dihydro-1H-quinolin-2-one (carteolol) (Compound)

Description: A compound in the knowledge graph

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 5-(3-tert-Butylamino-2-hydroxy-propoxy)-3,4-dihydro-1H-quinolin-2-one (carteolol)'s neighborhood in the knowledge graph.

Submit

Knowledge Graph Assertions

Source	Relation	Target	Evidence
5-(3-tert-Butylamino-2-hydroxy-propoxy)-3,4-dihydro-1H-quinolin-2-one (carteolol) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DLK1 Gene (Entity type)	-0.010648395
5-(3-tert-Butylamino-2-hydroxy-propoxy)-3,4-dihydro-1H-quinolin-2-one (carteolol) Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	naloxone Compound (Entity type)	0.2773299515247345
5-(3-tert-Butylamino-2-hydroxy-propoxy)-3,4-dihydro-1H-quinolin-2-one (carteolol) Compound (Entity type)	Indication Knowledge Graph Relation (Entity type)	Hypertensive disease Disease or Phenotype (Entity type)
5-(3-tert-Butylamino-2-hydroxy-propoxy)-3,4-dihydro-1H-quinolin-2-one (carteolol) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	RGS5 Gene (Entity type)	-0.010055766
5-(3-tert-Butylamino-2-hydroxy-propoxy)-3,4-dihydro-1H-quinolin-2-one (carteolol) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HNRNPL Gene (Entity type)	-0.008932632
5-(3-tert-Butylamino-2-hydroxy-propoxy)-3,4-dihydro-1H-quinolin-2-one (carteolol) Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PI3 Gene (Entity type)	0.010401153
5-(3-tert-Butylamino-2-hydroxy-propoxy)-3,4-dihydro-1H-quinolin-2-one (carteolol) Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DEFB1 Gene (Entity type)	0.009411304
5-(3-tert-Butylamino-2-hydroxy-propoxy)-3,4-dihydro-1H-quinolin-2-one (carteolol) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IFI6 Gene (Entity type)	-0.009639111
5-(3-tert-Butylamino-2-hydroxy-propoxy)-3,4-dihydro-1H-quinolin-2-one (carteolol) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MFSD12 Gene (Entity type)	-0.008269265
5-(3-tert-Butylamino-2-hydroxy-propoxy)-3,4-dihydro-1H-quinolin-2-one (carteolol) Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ZNF586 Gene (Entity type)	0.011169478

5-(3-tert-Butylamino-2-hydroxy-propoxy)-3,4-dihydro-1H-quinolin-2-one (carteolol)
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
DLK1
Gene (Entity type)
-0.010648395

5-(3-tert-Butylamino-2-hydroxy-propoxy)-3,4-dihydro-1H-quinolin-2-one (carteolol)
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
naloxone
Compound (Entity type)
0.2773299515247345

5-(3-tert-Butylamino-2-hydroxy-propoxy)-3,4-dihydro-1H-quinolin-2-one (carteolol)
Compound (Entity type)
Indication
Knowledge Graph Relation (Entity type)
Hypertensive disease
Disease or Phenotype (Entity type)

5-(3-tert-Butylamino-2-hydroxy-propoxy)-3,4-dihydro-1H-quinolin-2-one (carteolol)
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
RGS5
Gene (Entity type)
-0.010055766

5-(3-tert-Butylamino-2-hydroxy-propoxy)-3,4-dihydro-1H-quinolin-2-one (carteolol)
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HNRNPL
Gene (Entity type)
-0.008932632

5-(3-tert-Butylamino-2-hydroxy-propoxy)-3,4-dihydro-1H-quinolin-2-one (carteolol)
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PI3
Gene (Entity type)
0.010401153

5-(3-tert-Butylamino-2-hydroxy-propoxy)-3,4-dihydro-1H-quinolin-2-one (carteolol)
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
DEFB1
Gene (Entity type)
0.009411304

5-(3-tert-Butylamino-2-hydroxy-propoxy)-3,4-dihydro-1H-quinolin-2-one (carteolol)
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
IFI6
Gene (Entity type)
-0.009639111

5-(3-tert-Butylamino-2-hydroxy-propoxy)-3,4-dihydro-1H-quinolin-2-one (carteolol)
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MFSD12
Gene (Entity type)
-0.008269265

5-(3-tert-Butylamino-2-hydroxy-propoxy)-3,4-dihydro-1H-quinolin-2-one (carteolol)
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ZNF586
Gene (Entity type)
0.011169478

DISPLAY PER PAGE

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
Loading results...

DISPLAY PER PAGE

CFDE Workbench

Consortium

Community

Resources

@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.