5-(3-tert-Butylamino-2-hydroxy-propoxy)-3,4-dihydro-1H-quinolin-2-one (carteolol) (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 5-(3-tert-Butylamino-2-hydroxy-propoxy)-3,4-dihydro-1H-quinolin-2-one (carteolol)'s neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
5-(3-tert-Butylamino-2-hydroxy-propoxy)-3,4-dihydro-1H-quinolin-2-one (carteolol) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DLK1 Gene (Entity type)	-0.010648395
5-(3-tert-Butylamino-2-hydroxy-propoxy)-3,4-dihydro-1H-quinolin-2-one (carteolol) Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	naloxone Compound (Entity type)	0.2773299515247345
5-(3-tert-Butylamino-2-hydroxy-propoxy)-3,4-dihydro-1H-quinolin-2-one (carteolol) Compound (Entity type)	Indication Knowledge Graph Relation (Entity type)	Ocular Hypertension Disease or Phenotype (Entity type)
5-(3-tert-Butylamino-2-hydroxy-propoxy)-3,4-dihydro-1H-quinolin-2-one (carteolol) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	RGS5 Gene (Entity type)	-0.010055766
5-(3-tert-Butylamino-2-hydroxy-propoxy)-3,4-dihydro-1H-quinolin-2-one (carteolol) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HNRNPL Gene (Entity type)	-0.008932632
5-(3-tert-Butylamino-2-hydroxy-propoxy)-3,4-dihydro-1H-quinolin-2-one (carteolol) Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PI3 Gene (Entity type)	0.010401153
5-(3-tert-Butylamino-2-hydroxy-propoxy)-3,4-dihydro-1H-quinolin-2-one (carteolol) Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DEFB1 Gene (Entity type)	0.009411304
5-(3-tert-Butylamino-2-hydroxy-propoxy)-3,4-dihydro-1H-quinolin-2-one (carteolol) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IFI6 Gene (Entity type)	-0.009639111
5-(3-tert-Butylamino-2-hydroxy-propoxy)-3,4-dihydro-1H-quinolin-2-one (carteolol) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MFSD12 Gene (Entity type)	-0.008269265
5-(3-tert-Butylamino-2-hydroxy-propoxy)-3,4-dihydro-1H-quinolin-2-one (carteolol) Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ZNF586 Gene (Entity type)	0.011169478