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PF-477736 (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View PF-477736's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	PF-477736 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	EGR1 Gene (Entity type)	0.007784589
	PF-477736 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	LTBP2 Gene (Entity type)	-0.0059407195
	PF-477736 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NR4A2 Gene (Entity type)	0.0076353536
	(S)-1-(5-bromo-4-methyl-2-(morpholin-2-ylmethoxy)phenyl)-3-(5-methylpyrazin-2-yl)urea Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	PF-477736 Compound (Entity type)	0.4625485837459564
	PF-477736 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	BTG2 Gene (Entity type)	0.006644167
	PF-477736 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	(S)-1-(5-bromo-4-methyl-2-(morpholin-2-ylmethoxy)phenyl)-3-(5-methylpyrazin-2-yl)urea Compound (Entity type)	0.4625485837459564
	PF-477736 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	JUNB Gene (Entity type)	0.0069404575
	PF-477736 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CDKN1A Gene (Entity type)	0.012475763
	PF-477736 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	RCAN2 Gene (Entity type)	-0.0056705764
	PF-477736 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ENO2 Gene (Entity type)	-0.0060905875

PF-477736
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
EGR1
Gene (Entity type)
0.007784589

PF-477736
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
LTBP2
Gene (Entity type)
-0.0059407195

PF-477736
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
NR4A2
Gene (Entity type)
0.0076353536

(S)-1-(5-bromo-4-methyl-2-(morpholin-2-ylmethoxy)phenyl)-3-(5-methylpyrazin-2-yl)urea
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
PF-477736
Compound (Entity type)
0.4625485837459564

PF-477736
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
BTG2
Gene (Entity type)
0.006644167

PF-477736
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
(S)-1-(5-bromo-4-methyl-2-(morpholin-2-ylmethoxy)phenyl)-3-(5-methylpyrazin-2-yl)urea
Compound (Entity type)
0.4625485837459564

PF-477736
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
JUNB
Gene (Entity type)
0.0069404575

PF-477736
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CDKN1A
Gene (Entity type)
0.012475763

PF-477736
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
RCAN2
Gene (Entity type)
-0.0056705764

PF-477736
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ENO2
Gene (Entity type)
-0.0060905875

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