(1R,2S)-2-(3-((E)-4-((S)-1-Morpholinoethyl)styryl)-1H-indazol-6-yl)spiro[cyclopropane-1,3'-indolin]-2'-one (Compound)

Description: A compound in the knowledge graph

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View (1R,2S)-2-(3-((E)-4-((S)-1-Morpholinoethyl)styryl)-1H-indazol-6-yl)spiro[cyclopropane-1,3'-indolin]-2'-one's neighborhood in the knowledge graph.

Submit

Knowledge Graph Assertions

Source	Relation	Target	Evidence
(1R,2S)-2-(3-((E)-4-((S)-1-Morpholinoethyl)styryl)-1H-indazol-6-yl)spiro[cyclopropane-1,3'-indolin]-2'-one Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Serine/threonine-protein kinase PLK4 Protein (Entity type)	IC50
(1R,2S)-2-(3-((E)-4-((S)-1-Morpholinoethyl)styryl)-1H-indazol-6-yl)spiro[cyclopropane-1,3'-indolin]-2'-one Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Cytochrome P450 3A4 Protein (Entity type)	IC50
(1R,2S)-2-(3-((E)-4-((S)-1-Morpholinoethyl)styryl)-1H-indazol-6-yl)spiro[cyclopropane-1,3'-indolin]-2'-one Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Cytochrome P450 2C9 Protein (Entity type)	IC50
(1R,2S)-2-(3-((E)-4-((S)-1-Morpholinoethyl)styryl)-1H-indazol-6-yl)spiro[cyclopropane-1,3'-indolin]-2'-one Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Cytochrome P450 2C19 Protein (Entity type)	IC50

(1R,2S)-2-(3-((E)-4-((S)-1-Morpholinoethyl)styryl)-1H-indazol-6-yl)spiro[cyclopropane-1,3'-indolin]-2'-one
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Serine/threonine-protein kinase PLK4
Protein (Entity type)
IC50

(1R,2S)-2-(3-((E)-4-((S)-1-Morpholinoethyl)styryl)-1H-indazol-6-yl)spiro[cyclopropane-1,3'-indolin]-2'-one
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Cytochrome P450 3A4
Protein (Entity type)
IC50

(1R,2S)-2-(3-((E)-4-((S)-1-Morpholinoethyl)styryl)-1H-indazol-6-yl)spiro[cyclopropane-1,3'-indolin]-2'-one
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Cytochrome P450 2C9
Protein (Entity type)
IC50

(1R,2S)-2-(3-((E)-4-((S)-1-Morpholinoethyl)styryl)-1H-indazol-6-yl)spiro[cyclopropane-1,3'-indolin]-2'-one
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Cytochrome P450 2C19
Protein (Entity type)
IC50

DISPLAY PER PAGE

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
Loading results...

DISPLAY PER PAGE

CFDE Workbench

Consortium

Community

Resources

@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.