(1R,2S)-2-(3-((E)-4-((S)-1-Morpholinoethyl)styryl)-1H-indazol-6-yl)spiro[cyclopropane-1,3'-indolin]-2'-one (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View (1R,2S)-2-(3-((E)-4-((S)-1-Morpholinoethyl)styryl)-1H-indazol-6-yl)spiro[cyclopropane-1,3'-indolin]-2'-one's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
(1R,2S)-2-(3-((E)-4-((S)-1-Morpholinoethyl)styryl)-1H-indazol-6-yl)spiro[cyclopropane-1,3'-indolin]-2'-one Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Serine/threonine-protein kinase PLK4 Protein (Entity type)	IC50
(1R,2S)-2-(3-((E)-4-((S)-1-Morpholinoethyl)styryl)-1H-indazol-6-yl)spiro[cyclopropane-1,3'-indolin]-2'-one Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Cytochrome P450 3A4 Protein (Entity type)	IC50
(1R,2S)-2-(3-((E)-4-((S)-1-Morpholinoethyl)styryl)-1H-indazol-6-yl)spiro[cyclopropane-1,3'-indolin]-2'-one Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Cytochrome P450 2C9 Protein (Entity type)	IC50
(1R,2S)-2-(3-((E)-4-((S)-1-Morpholinoethyl)styryl)-1H-indazol-6-yl)spiro[cyclopropane-1,3'-indolin]-2'-one Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Cytochrome P450 2C19 Protein (Entity type)	IC50