1-(2,3,4-trimethoxybenzyl)-4-(bis(4-fluorophenyl)methyl)piperazine (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 1-(2,3,4-trimethoxybenzyl)-4-(bis(4-fluorophenyl)methyl)piperazine's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
Phenylbutazone Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	1-(2,3,4-trimethoxybenzyl)-4-(bis(4-fluorophenyl)methyl)piperazine Compound (Entity type)	0.3580341041088104
1-(2,3,4-trimethoxybenzyl)-4-(bis(4-fluorophenyl)methyl)piperazine Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Voltage-dependent N-type calcium channel subunit alpha-1B Protein (Entity type)	IC50
1-(2,3,4-trimethoxybenzyl)-4-(bis(4-fluorophenyl)methyl)piperazine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	GNAS Gene (Entity type)	0.0034564952
1-(2,3,4-trimethoxybenzyl)-4-(bis(4-fluorophenyl)methyl)piperazine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MET Gene (Entity type)	-0.0027518002
1-(2,3,4-trimethoxybenzyl)-4-(bis(4-fluorophenyl)methyl)piperazine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MMP12 Gene (Entity type)	0.0031328152
Pirlindole Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	1-(2,3,4-trimethoxybenzyl)-4-(bis(4-fluorophenyl)methyl)piperazine Compound (Entity type)	0.2408148050308227
1-(2,3,4-trimethoxybenzyl)-4-(bis(4-fluorophenyl)methyl)piperazine Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Bitopertin Compound (Entity type)	0.4061519801616668
1-(2,3,4-trimethoxybenzyl)-4-(bis(4-fluorophenyl)methyl)piperazine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	NUPR1 Gene (Entity type)	-0.0025374787
1-(2,3,4-trimethoxybenzyl)-4-(bis(4-fluorophenyl)methyl)piperazine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SKIC2 Gene (Entity type)	-0.0027606897
Empagliflozin Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	1-(2,3,4-trimethoxybenzyl)-4-(bis(4-fluorophenyl)methyl)piperazine Compound (Entity type)	0.322153240442276