2'-(4-ethoxyphenyl)-5-(4-methylpiperazin-1-yl)-1H,1'H-2,5'-bibenzo[d]imidazole (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 2'-(4-ethoxyphenyl)-5-(4-methylpiperazin-1-yl)-1H,1'H-2,5'-bibenzo[d]imidazole's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
2'-(4-ethoxyphenyl)-5-(4-methylpiperazin-1-yl)-1H,1'H-2,5'-bibenzo[d]imidazole Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	AKR1C2 Gene (Entity type)	-0.01142336
2'-(4-ethoxyphenyl)-5-(4-methylpiperazin-1-yl)-1H,1'H-2,5'-bibenzo[d]imidazole Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	ER-27319 Compound (Entity type)	0.3119096159934997
2'-(4-ethoxyphenyl)-5-(4-methylpiperazin-1-yl)-1H,1'H-2,5'-bibenzo[d]imidazole Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TGM2 Gene (Entity type)	0.009691823
2'-(4-ethoxyphenyl)-5-(4-methylpiperazin-1-yl)-1H,1'H-2,5'-bibenzo[d]imidazole Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ATF3 Gene (Entity type)	0.00867755
2'-(4-ethoxyphenyl)-5-(4-methylpiperazin-1-yl)-1H,1'H-2,5'-bibenzo[d]imidazole Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CEACAM6 Gene (Entity type)	-0.016068077
2'-(4-ethoxyphenyl)-5-(4-methylpiperazin-1-yl)-1H,1'H-2,5'-bibenzo[d]imidazole Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	triptolide Compound (Entity type)	0.326473206281662
2'-(4-ethoxyphenyl)-5-(4-methylpiperazin-1-yl)-1H,1'H-2,5'-bibenzo[d]imidazole Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	L1CAM Gene (Entity type)	0.013203249
2'-(4-ethoxyphenyl)-5-(4-methylpiperazin-1-yl)-1H,1'H-2,5'-bibenzo[d]imidazole Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CPS1 Gene (Entity type)	0.009130953
2'-(4-ethoxyphenyl)-5-(4-methylpiperazin-1-yl)-1H,1'H-2,5'-bibenzo[d]imidazole Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	THBS2 Gene (Entity type)	0.008838398
2'-(4-ethoxyphenyl)-5-(4-methylpiperazin-1-yl)-1H,1'H-2,5'-bibenzo[d]imidazole Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	GPNMB Gene (Entity type)	-0.010360451

2'-(4-ethoxyphenyl)-5-(4-methylpiperazin-1-yl)-1H,1'H-2,5'-bibenzo[d]imidazole
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
AKR1C2
Gene (Entity type)
-0.01142336

2'-(4-ethoxyphenyl)-5-(4-methylpiperazin-1-yl)-1H,1'H-2,5'-bibenzo[d]imidazole
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
ER-27319
Compound (Entity type)
0.3119096159934997

2'-(4-ethoxyphenyl)-5-(4-methylpiperazin-1-yl)-1H,1'H-2,5'-bibenzo[d]imidazole
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TGM2
Gene (Entity type)
0.009691823

2'-(4-ethoxyphenyl)-5-(4-methylpiperazin-1-yl)-1H,1'H-2,5'-bibenzo[d]imidazole
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ATF3
Gene (Entity type)
0.00867755

2'-(4-ethoxyphenyl)-5-(4-methylpiperazin-1-yl)-1H,1'H-2,5'-bibenzo[d]imidazole
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CEACAM6
Gene (Entity type)
-0.016068077

2'-(4-ethoxyphenyl)-5-(4-methylpiperazin-1-yl)-1H,1'H-2,5'-bibenzo[d]imidazole
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
triptolide
Compound (Entity type)
0.326473206281662

2'-(4-ethoxyphenyl)-5-(4-methylpiperazin-1-yl)-1H,1'H-2,5'-bibenzo[d]imidazole
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
L1CAM
Gene (Entity type)
0.013203249

2'-(4-ethoxyphenyl)-5-(4-methylpiperazin-1-yl)-1H,1'H-2,5'-bibenzo[d]imidazole
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CPS1
Gene (Entity type)
0.009130953

2'-(4-ethoxyphenyl)-5-(4-methylpiperazin-1-yl)-1H,1'H-2,5'-bibenzo[d]imidazole
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
THBS2
Gene (Entity type)
0.008838398

2'-(4-ethoxyphenyl)-5-(4-methylpiperazin-1-yl)-1H,1'H-2,5'-bibenzo[d]imidazole
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
GPNMB
Gene (Entity type)
-0.010360451

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