1-[9-(4-Chlorophenyl)-8-(2-chlorophenyl)-9H-purin-6-yl]-4-ethylaminopiperidine-4-carboxylic Acid Amide Hydrochloride (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 1-[9-(4-Chlorophenyl)-8-(2-chlorophenyl)-9H-purin-6-yl]-4-ethylaminopiperidine-4-carboxylic Acid Amide Hydrochloride's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
1-[9-(4-Chlorophenyl)-8-(2-chlorophenyl)-9H-purin-6-yl]-4-ethylaminopiperidine-4-carboxylic Acid Amide Hydrochloride Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CLEC11A Gene (Entity type)	0.0044668014
1-[9-(4-Chlorophenyl)-8-(2-chlorophenyl)-9H-purin-6-yl]-4-ethylaminopiperidine-4-carboxylic Acid Amide Hydrochloride Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MAP7 Gene (Entity type)	-0.0067826887
1-[9-(4-Chlorophenyl)-8-(2-chlorophenyl)-9H-purin-6-yl]-4-ethylaminopiperidine-4-carboxylic Acid Amide Hydrochloride Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IDE Gene (Entity type)	-0.006283625
1-[9-(4-Chlorophenyl)-8-(2-chlorophenyl)-9H-purin-6-yl]-4-ethylaminopiperidine-4-carboxylic Acid Amide Hydrochloride Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SIK1 Gene (Entity type)	-0.005046482
1-[9-(4-Chlorophenyl)-8-(2-chlorophenyl)-9H-purin-6-yl]-4-ethylaminopiperidine-4-carboxylic Acid Amide Hydrochloride Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Tolcapone Compound (Entity type)	0.3047218024730682
1-[9-(4-Chlorophenyl)-8-(2-chlorophenyl)-9H-purin-6-yl]-4-ethylaminopiperidine-4-carboxylic Acid Amide Hydrochloride Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	GAPDH Gene (Entity type)	0.009036642
Levofloxacin Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	1-[9-(4-Chlorophenyl)-8-(2-chlorophenyl)-9H-purin-6-yl]-4-ethylaminopiperidine-4-carboxylic Acid Amide Hydrochloride Compound (Entity type)	0.4605401754379272
1-[9-(4-Chlorophenyl)-8-(2-chlorophenyl)-9H-purin-6-yl]-4-ethylaminopiperidine-4-carboxylic Acid Amide Hydrochloride Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CDK14 Gene (Entity type)	0.0045004133
1-[9-(4-Chlorophenyl)-8-(2-chlorophenyl)-9H-purin-6-yl]-4-ethylaminopiperidine-4-carboxylic Acid Amide Hydrochloride Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HSPA4L Gene (Entity type)	-0.004529254
1-[9-(4-Chlorophenyl)-8-(2-chlorophenyl)-9H-purin-6-yl]-4-ethylaminopiperidine-4-carboxylic Acid Amide Hydrochloride Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TPD52 Gene (Entity type)	-0.0059461514

1-[9-(4-Chlorophenyl)-8-(2-chlorophenyl)-9H-purin-6-yl]-4-ethylaminopiperidine-4-carboxylic Acid Amide Hydrochloride
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CLEC11A
Gene (Entity type)
0.0044668014

1-[9-(4-Chlorophenyl)-8-(2-chlorophenyl)-9H-purin-6-yl]-4-ethylaminopiperidine-4-carboxylic Acid Amide Hydrochloride
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MAP7
Gene (Entity type)
-0.0067826887

1-[9-(4-Chlorophenyl)-8-(2-chlorophenyl)-9H-purin-6-yl]-4-ethylaminopiperidine-4-carboxylic Acid Amide Hydrochloride
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
IDE
Gene (Entity type)
-0.006283625

1-[9-(4-Chlorophenyl)-8-(2-chlorophenyl)-9H-purin-6-yl]-4-ethylaminopiperidine-4-carboxylic Acid Amide Hydrochloride
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SIK1
Gene (Entity type)
-0.005046482

1-[9-(4-Chlorophenyl)-8-(2-chlorophenyl)-9H-purin-6-yl]-4-ethylaminopiperidine-4-carboxylic Acid Amide Hydrochloride
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Tolcapone
Compound (Entity type)
0.3047218024730682

1-[9-(4-Chlorophenyl)-8-(2-chlorophenyl)-9H-purin-6-yl]-4-ethylaminopiperidine-4-carboxylic Acid Amide Hydrochloride
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
GAPDH
Gene (Entity type)
0.009036642

Levofloxacin
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
1-[9-(4-Chlorophenyl)-8-(2-chlorophenyl)-9H-purin-6-yl]-4-ethylaminopiperidine-4-carboxylic Acid Amide Hydrochloride
Compound (Entity type)
0.4605401754379272

1-[9-(4-Chlorophenyl)-8-(2-chlorophenyl)-9H-purin-6-yl]-4-ethylaminopiperidine-4-carboxylic Acid Amide Hydrochloride
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CDK14
Gene (Entity type)
0.0045004133

1-[9-(4-Chlorophenyl)-8-(2-chlorophenyl)-9H-purin-6-yl]-4-ethylaminopiperidine-4-carboxylic Acid Amide Hydrochloride
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HSPA4L
Gene (Entity type)
-0.004529254

1-[9-(4-Chlorophenyl)-8-(2-chlorophenyl)-9H-purin-6-yl]-4-ethylaminopiperidine-4-carboxylic Acid Amide Hydrochloride
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TPD52
Gene (Entity type)
-0.0059461514

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