(R)-1-((2S,3R)-3-hydroxy-2-(6-phenylpicolinamido)butanamido)-3-methylbutylboronic acid (Compound)

Description: A compound in the knowledge graph

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View (R)-1-((2S,3R)-3-hydroxy-2-(6-phenylpicolinamido)butanamido)-3-methylbutylboronic acid's neighborhood in the knowledge graph.

Submit

Knowledge Graph Assertions

Source	Relation	Target	Evidence
Metronidazole Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	(R)-1-((2S,3R)-3-hydroxy-2-(6-phenylpicolinamido)butanamido)-3-methylbutylboronic acid Compound (Entity type)	0.4165642559528351
oprozomib Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	(R)-1-((2S,3R)-3-hydroxy-2-(6-phenylpicolinamido)butanamido)-3-methylbutylboronic acid Compound (Entity type)	0.8753569722175598
(R)-1-((2S,3R)-3-hydroxy-2-(6-phenylpicolinamido)butanamido)-3-methylbutylboronic acid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	NT5E Gene (Entity type)	-0.011384622
(R)-1-((2S,3R)-3-hydroxy-2-(6-phenylpicolinamido)butanamido)-3-methylbutylboronic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HSPA1A Gene (Entity type)	0.012551081
(R)-1-((2S,3R)-3-hydroxy-2-(6-phenylpicolinamido)butanamido)-3-methylbutylboronic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Proteasome subunit beta type-9 Protein (Entity type)	IC50
(R)-1-((2S,3R)-3-hydroxy-2-(6-phenylpicolinamido)butanamido)-3-methylbutylboronic acid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	XYLT1 Gene (Entity type)	-0.010223424
(R)-1-((2S,3R)-3-hydroxy-2-(6-phenylpicolinamido)butanamido)-3-methylbutylboronic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MAN2B1 Gene (Entity type)	0.012512508
(R)-1-((2S,3R)-3-hydroxy-2-(6-phenylpicolinamido)butanamido)-3-methylbutylboronic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NIBAN1 Gene (Entity type)	0.016333437
(R)-1-((2S,3R)-3-hydroxy-2-(6-phenylpicolinamido)butanamido)-3-methylbutylboronic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	AKR1C1 Gene (Entity type)	0.017776396
(R)-1-((2S,3R)-3-hydroxy-2-(6-phenylpicolinamido)butanamido)-3-methylbutylboronic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Proteasome subunit beta type-5 Protein (Entity type)	IC50

Metronidazole
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
(R)-1-((2S,3R)-3-hydroxy-2-(6-phenylpicolinamido)butanamido)-3-methylbutylboronic acid
Compound (Entity type)
0.4165642559528351

oprozomib
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
(R)-1-((2S,3R)-3-hydroxy-2-(6-phenylpicolinamido)butanamido)-3-methylbutylboronic acid
Compound (Entity type)
0.8753569722175598

(R)-1-((2S,3R)-3-hydroxy-2-(6-phenylpicolinamido)butanamido)-3-methylbutylboronic acid
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
NT5E
Gene (Entity type)
-0.011384622

(R)-1-((2S,3R)-3-hydroxy-2-(6-phenylpicolinamido)butanamido)-3-methylbutylboronic acid
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
HSPA1A
Gene (Entity type)
0.012551081

(R)-1-((2S,3R)-3-hydroxy-2-(6-phenylpicolinamido)butanamido)-3-methylbutylboronic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Proteasome subunit beta type-9
Protein (Entity type)
IC50

(R)-1-((2S,3R)-3-hydroxy-2-(6-phenylpicolinamido)butanamido)-3-methylbutylboronic acid
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
XYLT1
Gene (Entity type)
-0.010223424

(R)-1-((2S,3R)-3-hydroxy-2-(6-phenylpicolinamido)butanamido)-3-methylbutylboronic acid
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MAN2B1
Gene (Entity type)
0.012512508

(R)-1-((2S,3R)-3-hydroxy-2-(6-phenylpicolinamido)butanamido)-3-methylbutylboronic acid
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
NIBAN1
Gene (Entity type)
0.016333437

(R)-1-((2S,3R)-3-hydroxy-2-(6-phenylpicolinamido)butanamido)-3-methylbutylboronic acid
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
AKR1C1
Gene (Entity type)
0.017776396

(R)-1-((2S,3R)-3-hydroxy-2-(6-phenylpicolinamido)butanamido)-3-methylbutylboronic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Proteasome subunit beta type-5
Protein (Entity type)
IC50

DISPLAY PER PAGE

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
Loading results...

DISPLAY PER PAGE

CFDE Workbench

Consortium

Community

Resources

@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.