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oprozomib (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View oprozomib's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	oprozomib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ATF3 Gene (Entity type)	0.012550629
	oprozomib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MAGEA3 Gene (Entity type)	-0.010115151
	oprozomib Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	(R)-1-((2S,3R)-3-hydroxy-2-(6-phenylpicolinamido)butanamido)-3-methylbutylboronic acid Compound (Entity type)	0.8753569722175598
	oprozomib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DNM1 Gene (Entity type)	0.012548969
	oprozomib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	KRT19 Gene (Entity type)	-0.010346941
	((1S,2S,4R)-4-(4-((S)-2,3-dihydro-1H-inden-1-ylamino)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-hydroxycyclopentyl)methyl sulfamate Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	oprozomib Compound (Entity type)	0.4490664899349212
	oprozomib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TUBB2B Gene (Entity type)	0.0116484985
	oprozomib Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Thiostrepton Compound (Entity type)	0.516416609287262
	oprozomib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CYB5R1 Gene (Entity type)	0.011623614
	oprozomib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ME1 Gene (Entity type)	0.011912186

oprozomib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ATF3
Gene (Entity type)
0.012550629

oprozomib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MAGEA3
Gene (Entity type)
-0.010115151

oprozomib
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
(R)-1-((2S,3R)-3-hydroxy-2-(6-phenylpicolinamido)butanamido)-3-methylbutylboronic acid
Compound (Entity type)
0.8753569722175598

oprozomib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
DNM1
Gene (Entity type)
0.012548969

oprozomib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
KRT19
Gene (Entity type)
-0.010346941

((1S,2S,4R)-4-(4-((S)-2,3-dihydro-1H-inden-1-ylamino)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-hydroxycyclopentyl)methyl sulfamate
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
oprozomib
Compound (Entity type)
0.4490664899349212

oprozomib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TUBB2B
Gene (Entity type)
0.0116484985

oprozomib
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Thiostrepton
Compound (Entity type)
0.516416609287262

oprozomib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CYB5R1
Gene (Entity type)
0.011623614

oprozomib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ME1
Gene (Entity type)
0.011912186

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