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ICI-162846 (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View ICI-162846's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	Propylthiouracil Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	ICI-162846 Compound (Entity type)	0.4274305999279022
	ICI-162846 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	gemfibrozil Compound (Entity type)	0.591850221157074
	ICI-162846 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	NFATC3 Gene (Entity type)	-0.005855689
	ICI-162846 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PTCH1 Gene (Entity type)	-0.004687063
	SB-683698 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	ICI-162846 Compound (Entity type)	0.5726817846298218
	sulfamic acid (3aS,5aR,8aR,8bS)-2,2,7,7-tetramethyl-tetrahydro-benzo[1,2-d,3,4-d']bis[1,3]dioxol-3a-ylmethyl ester Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	ICI-162846 Compound (Entity type)	0.5508617758750916
	2-Hydroxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydro-indolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carboxylic acid methyl ester (Yohimbine) Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	ICI-162846 Compound (Entity type)	0.571419358253479
	CPI-1189 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	ICI-162846 Compound (Entity type)	0.5366177558898926
	ICI-162846 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	S100A8 Gene (Entity type)	0.0065047597
	ICI-162846 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Granisetron Compound (Entity type)	0.6316555142402649

Propylthiouracil
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
ICI-162846
Compound (Entity type)
0.4274305999279022

ICI-162846
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
gemfibrozil
Compound (Entity type)
0.591850221157074

ICI-162846
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
NFATC3
Gene (Entity type)
-0.005855689

ICI-162846
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PTCH1
Gene (Entity type)
-0.004687063

SB-683698
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
ICI-162846
Compound (Entity type)
0.5726817846298218

sulfamic acid (3aS,5aR,8aR,8bS)-2,2,7,7-tetramethyl-tetrahydro-benzo[1,2-d,3,4-d']bis[1,3]dioxol-3a-ylmethyl ester
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
ICI-162846
Compound (Entity type)
0.5508617758750916

2-Hydroxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydro-indolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carboxylic acid methyl ester (Yohimbine)
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
ICI-162846
Compound (Entity type)
0.571419358253479

CPI-1189
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
ICI-162846
Compound (Entity type)
0.5366177558898926

ICI-162846
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
S100A8
Gene (Entity type)
0.0065047597

ICI-162846
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Granisetron
Compound (Entity type)
0.6316555142402649

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