3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile (Compound)

Description: A compound in the knowledge graph

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile's neighborhood in the knowledge graph.

Submit

Knowledge Graph Assertions

Source	Relation	Target	Evidence
3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SOX11 Gene (Entity type)	0.0042750454
3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Serine/threonine-protein kinase DCLK3 Protein (Entity type)	Kd
3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Non-receptor tyrosine-protein kinase TYK2 Protein (Entity type)	IC50
AT1-SHH-09 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile Compound (Entity type)	0.3757528960704803
3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IER3 Gene (Entity type)	-0.004921568
3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TGM2 Gene (Entity type)	0.0038349794
3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CYP1B1 Gene (Entity type)	-0.0057032616
3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Serine/threonine-protein kinase N1 Protein (Entity type)	IC50
3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SLC1A3 Gene (Entity type)	0.00395695
Allantoin Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile Compound (Entity type)	0.3355565965175628

3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SOX11
Gene (Entity type)
0.0042750454

3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Serine/threonine-protein kinase DCLK3
Protein (Entity type)
Kd

3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Non-receptor tyrosine-protein kinase TYK2
Protein (Entity type)
IC50

AT1-SHH-09
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile
Compound (Entity type)
0.3757528960704803

3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
IER3
Gene (Entity type)
-0.004921568

3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TGM2
Gene (Entity type)
0.0038349794

3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CYP1B1
Gene (Entity type)
-0.0057032616

3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Serine/threonine-protein kinase N1
Protein (Entity type)
IC50

3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SLC1A3
Gene (Entity type)
0.00395695

Allantoin
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile
Compound (Entity type)
0.3355565965175628

DISPLAY PER PAGE

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
Loading results...

DISPLAY PER PAGE

CFDE Workbench

Consortium

Community

Resources

@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.