3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SOX11 Gene (Entity type)	0.0042750454
3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Serine/threonine-protein kinase DCLK3 Protein (Entity type)	Kd
3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Non-receptor tyrosine-protein kinase TYK2 Protein (Entity type)	IC50
AT1-SHH-09 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile Compound (Entity type)	0.3757528960704803
3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IER3 Gene (Entity type)	-0.004921568
3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TGM2 Gene (Entity type)	0.0038349794
3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CYP1B1 Gene (Entity type)	-0.0057032616
3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Serine/threonine-protein kinase N1 Protein (Entity type)	IC50
3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SLC1A3 Gene (Entity type)	0.00395695
Allantoin Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile Compound (Entity type)	0.3355565965175628