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Serine/threonine-protein kinase N1 (Protein)

Description: A protein in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Serine/threonine-protein kinase N1 's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Serine/threonine-protein kinase N1 Protein (Entity type)	IC50
	RKI-1447 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Serine/threonine-protein kinase N1 Protein (Entity type)	IC50
	16-hydroxy-16-(hydroxymethyl)-15-methyl-28-oxa-4,14,19-triazaoctacyclo[12.11.2.1^{15,18}.0^{2,6}.0^{7,27}.0^{8,13}.0^{19,26}.0^{20,25}]octacosa-1(26),2(6),7(27),8(13),9,11,20(25),21,23-nonaen-3-one Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Serine/threonine-protein kinase N1 Protein (Entity type)	Kd
	PUBCHEM:155552127 CUI Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Serine/threonine-protein kinase N1 Protein (Entity type)	Kd
	AT-13148 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Serine/threonine-protein kinase N1 Protein (Entity type)	Kd
	SAR-407899 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Serine/threonine-protein kinase N1 Protein (Entity type)	Kd
	Serine/threonine-protein kinase N1 Protein (Entity type)	Has isoform Knowledge Graph Relation (Entity type)	UNIPROTKB.ISOFORM:Q16512-1 CUI Isoform (Entity type)
	UCN-01 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Serine/threonine-protein kinase N1 Protein (Entity type)	Kd
	[3-{2-[(3,5-Dimethyl-1H-pyrrol-2-yl-kappaN)methylidene]-2H-pyrrol-5-yl-kappaN}-N-(2-{2-[2-(2-{[(5S,6R,7R,9R)-6-methoxy-5-methyl-14-oxo-6,7,8,9,15,16-hexahydro-5H,14H-5,9-epoxy-4b,9a,15-triazadibenzo[b,h]cyclonona[1,2,3,4-jkl]cyclopenta[e]-as-indacen-7-yl]amino}ethoxy)ethoxy]ethoxy}ethyl)propanamidato](difluoro)borone Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Serine/threonine-protein kinase N1 Protein (Entity type)	Kd
	XL-228 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Serine/threonine-protein kinase N1 Protein (Entity type)	Kd

3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Serine/threonine-protein kinase N1
Protein (Entity type)
IC50

RKI-1447
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Serine/threonine-protein kinase N1
Protein (Entity type)
IC50

16-hydroxy-16-(hydroxymethyl)-15-methyl-28-oxa-4,14,19-triazaoctacyclo[12.11.2.1^{15,18}.0^{2,6}.0^{7,27}.0^{8,13}.0^{19,26}.0^{20,25}]octacosa-1(26),2(6),7(27),8(13),9,11,20(25),21,23-nonaen-3-one
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Serine/threonine-protein kinase N1
Protein (Entity type)
Kd

PUBCHEM:155552127 CUI
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Serine/threonine-protein kinase N1
Protein (Entity type)
Kd

AT-13148
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Serine/threonine-protein kinase N1
Protein (Entity type)
Kd

SAR-407899
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Serine/threonine-protein kinase N1
Protein (Entity type)
Kd

Serine/threonine-protein kinase N1
Protein (Entity type)
Has isoform
Knowledge Graph Relation (Entity type)
UNIPROTKB.ISOFORM:Q16512-1 CUI
Isoform (Entity type)

UCN-01
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Serine/threonine-protein kinase N1
Protein (Entity type)
Kd

[3-{2-[(3,5-Dimethyl-1H-pyrrol-2-yl-kappaN)methylidene]-2H-pyrrol-5-yl-kappaN}-N-(2-{2-[2-(2-{[(5S,6R,7R,9R)-6-methoxy-5-methyl-14-oxo-6,7,8,9,15,16-hexahydro-5H,14H-5,9-epoxy-4b,9a,15-triazadibenzo[b,h]cyclonona[1,2,3,4-jkl]cyclopenta[e]-as-indacen-7-yl]amino}ethoxy)ethoxy]ethoxy}ethyl)propanamidato](difluoro)borone
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Serine/threonine-protein kinase N1
Protein (Entity type)
Kd

XL-228
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Serine/threonine-protein kinase N1
Protein (Entity type)
Kd

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