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nintedanib (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View nintedanib's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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Tools & Use Cases

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	nintedanib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ARNT2 Gene (Entity type)	0.0038183588
	nintedanib Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Fibroblast growth factor receptor 1 Protein (Entity type)	IC50
	nintedanib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	LSM5 Gene (Entity type)	-0.0033331153
	nintedanib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CXCL10 Gene (Entity type)	0.0037829583
	nintedanib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	RNF167 Gene (Entity type)	-0.0034999768
	nintedanib Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	flumatinib Compound (Entity type)	0.3227360546588897
	nintedanib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	S100A8 Gene (Entity type)	0.0041692713
	nintedanib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	EGR1 Gene (Entity type)	-0.004610436
	nintedanib Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Cabozantinib Compound (Entity type)	0.34546560049057
	nintedanib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	BASP1 Gene (Entity type)	0.0044556605

nintedanib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ARNT2
Gene (Entity type)
0.0038183588

nintedanib
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Fibroblast growth factor receptor 1
Protein (Entity type)
IC50

nintedanib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
LSM5
Gene (Entity type)
-0.0033331153

nintedanib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CXCL10
Gene (Entity type)
0.0037829583

nintedanib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
RNF167
Gene (Entity type)
-0.0034999768

nintedanib
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
flumatinib
Compound (Entity type)
0.3227360546588897

nintedanib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
S100A8
Gene (Entity type)
0.0041692713

nintedanib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
EGR1
Gene (Entity type)
-0.004610436

nintedanib
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Cabozantinib
Compound (Entity type)
0.34546560049057

nintedanib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
BASP1
Gene (Entity type)
0.0044556605

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