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Cabozantinib (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Cabozantinib's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	Cabozantinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TNFAIP3 Gene (Entity type)	-0.0031534343
	Cabozantinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CPE Gene (Entity type)	0.0032683853
	Cabozantinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	EMP1 Gene (Entity type)	-0.0035469853
	Cabozantinib Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Mast/stem cell growth factor receptor Kit Protein (Entity type)	IC50
	Cabozantinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TMT1A Gene (Entity type)	0.0040026805
	Cabozantinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PI3 Gene (Entity type)	-0.004524196
	Cabozantinib Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Vascular endothelial growth factor receptor 1 Protein (Entity type)	IC50
	nintedanib Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Cabozantinib Compound (Entity type)	0.34546560049057
	EXEL-2880/GSK-1363089 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Cabozantinib Compound (Entity type)	0.4209901392459869
	Cabozantinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ASPN Gene (Entity type)	0.003208288

Cabozantinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TNFAIP3
Gene (Entity type)
-0.0031534343

Cabozantinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CPE
Gene (Entity type)
0.0032683853

Cabozantinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
EMP1
Gene (Entity type)
-0.0035469853

Cabozantinib
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Mast/stem cell growth factor receptor Kit
Protein (Entity type)
IC50

Cabozantinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TMT1A
Gene (Entity type)
0.0040026805

Cabozantinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PI3
Gene (Entity type)
-0.004524196

Cabozantinib
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Vascular endothelial growth factor receptor 1
Protein (Entity type)
IC50

nintedanib
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Cabozantinib
Compound (Entity type)
0.34546560049057

EXEL-2880/GSK-1363089
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Cabozantinib
Compound (Entity type)
0.4209901392459869

Cabozantinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ASPN
Gene (Entity type)
0.003208288

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