N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-(4-(1-methyl-1H-indol-3-yl)pyrimidin-2-ylamino)phenyl)acrylamide (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-(4-(1-methyl-1H-indol-3-yl)pyrimidin-2-ylamino)phenyl)acrylamide's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-(4-(1-methyl-1H-indol-3-yl)pyrimidin-2-ylamino)phenyl)acrylamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MT1F Gene (Entity type)	-0.0028081792
N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-(4-(1-methyl-1H-indol-3-yl)pyrimidin-2-ylamino)phenyl)acrylamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CCNB2 Gene (Entity type)	-0.0035416838
N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-(4-(1-methyl-1H-indol-3-yl)pyrimidin-2-ylamino)phenyl)acrylamide Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	tenovin-6 Compound (Entity type)	0.4458618462085724
N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-(4-(1-methyl-1H-indol-3-yl)pyrimidin-2-ylamino)phenyl)acrylamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MT1M Gene (Entity type)	-0.0030937106
N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-(4-(1-methyl-1H-indol-3-yl)pyrimidin-2-ylamino)phenyl)acrylamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CSGALNACT1 Gene (Entity type)	-0.00361922
N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-(4-(1-methyl-1H-indol-3-yl)pyrimidin-2-ylamino)phenyl)acrylamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PRAME Gene (Entity type)	-0.0031763834
N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-(4-(1-methyl-1H-indol-3-yl)pyrimidin-2-ylamino)phenyl)acrylamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SC5D Gene (Entity type)	0.00361118
N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-(4-(1-methyl-1H-indol-3-yl)pyrimidin-2-ylamino)phenyl)acrylamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	BHLHE40 Gene (Entity type)	0.0035667827
N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-(4-(1-methyl-1H-indol-3-yl)pyrimidin-2-ylamino)phenyl)acrylamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ACAT2 Gene (Entity type)	0.0042994665
N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-(4-(1-methyl-1H-indol-3-yl)pyrimidin-2-ylamino)phenyl)acrylamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MSMO1 Gene (Entity type)	0.005385962

N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-(4-(1-methyl-1H-indol-3-yl)pyrimidin-2-ylamino)phenyl)acrylamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MT1F
Gene (Entity type)
-0.0028081792

N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-(4-(1-methyl-1H-indol-3-yl)pyrimidin-2-ylamino)phenyl)acrylamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CCNB2
Gene (Entity type)
-0.0035416838

N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-(4-(1-methyl-1H-indol-3-yl)pyrimidin-2-ylamino)phenyl)acrylamide
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
tenovin-6
Compound (Entity type)
0.4458618462085724

N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-(4-(1-methyl-1H-indol-3-yl)pyrimidin-2-ylamino)phenyl)acrylamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MT1M
Gene (Entity type)
-0.0030937106

N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-(4-(1-methyl-1H-indol-3-yl)pyrimidin-2-ylamino)phenyl)acrylamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CSGALNACT1
Gene (Entity type)
-0.00361922

N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-(4-(1-methyl-1H-indol-3-yl)pyrimidin-2-ylamino)phenyl)acrylamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PRAME
Gene (Entity type)
-0.0031763834

N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-(4-(1-methyl-1H-indol-3-yl)pyrimidin-2-ylamino)phenyl)acrylamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SC5D
Gene (Entity type)
0.00361118

N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-(4-(1-methyl-1H-indol-3-yl)pyrimidin-2-ylamino)phenyl)acrylamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
BHLHE40
Gene (Entity type)
0.0035667827

N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-(4-(1-methyl-1H-indol-3-yl)pyrimidin-2-ylamino)phenyl)acrylamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ACAT2
Gene (Entity type)
0.0042994665

N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-(4-(1-methyl-1H-indol-3-yl)pyrimidin-2-ylamino)phenyl)acrylamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MSMO1
Gene (Entity type)
0.005385962

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