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Sunitinib (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Sunitinib's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	Sunitinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NUPR1 Gene (Entity type)	0.0063470905
	Sunitinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DHCR24 Gene (Entity type)	0.00691664
	Sunitinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	EGR1 Gene (Entity type)	-0.0040965546
	Sunitinib Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Platelet-derived growth factor receptor beta Protein (Entity type)	Kd
	Sunitinib Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Ribosomal protein S6 kinase alpha-5 Protein (Entity type)	Kd
	Sunitinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PLAUR Gene (Entity type)	-0.004060617
	Sunitinib Compound (Entity type)	Indication Knowledge Graph Relation (Entity type)	Gastrointestinal Stromal Sarcoma Disease or Phenotype (Entity type)
	Sunitinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PSAT1 Gene (Entity type)	0.0100269215
	Sunitinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TRIB3 Gene (Entity type)	0.006253736
	Sunitinib Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Protein delta homolog 1 Protein (Entity type)	Ki

Sunitinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
NUPR1
Gene (Entity type)
0.0063470905

Sunitinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
DHCR24
Gene (Entity type)
0.00691664

Sunitinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
EGR1
Gene (Entity type)
-0.0040965546

Sunitinib
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Platelet-derived growth factor receptor beta
Protein (Entity type)
Kd

Sunitinib
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Ribosomal protein S6 kinase alpha-5
Protein (Entity type)
Kd

Sunitinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PLAUR
Gene (Entity type)
-0.004060617

Sunitinib
Compound (Entity type)
Indication
Knowledge Graph Relation (Entity type)
Gastrointestinal Stromal Sarcoma
Disease or Phenotype (Entity type)

Sunitinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PSAT1
Gene (Entity type)
0.0100269215

Sunitinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TRIB3
Gene (Entity type)
0.006253736

Sunitinib
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Protein delta homolog 1
Protein (Entity type)
Ki

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