4-[(4-Chlorophenyl)methyl]-2-({(2R)-1-[4-(4-{[3-(hexahydro-1H-azepin-1-yl)propyl]oxy}phenyl)butyl]-2-pyrrolidinyl}methyl)pyrido[3,4-d]pyridazin-1(2H)-one (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 4-[(4-Chlorophenyl)methyl]-2-({(2R)-1-[4-(4-{[3-(hexahydro-1H-azepin-1-yl)propyl]oxy}phenyl)butyl]-2-pyrrolidinyl}methyl)pyrido[3,4-d]pyridazin-1(2H)-one's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
4-[(4-Chlorophenyl)methyl]-2-({(2R)-1-[4-(4-{[3-(hexahydro-1H-azepin-1-yl)propyl]oxy}phenyl)butyl]-2-pyrrolidinyl}methyl)pyrido[3,4-d]pyridazin-1(2H)-one Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Alpha-1B adrenergic receptor Protein (Entity type)	Ki
4-[(4-Chlorophenyl)methyl]-2-({(2R)-1-[4-(4-{[3-(hexahydro-1H-azepin-1-yl)propyl]oxy}phenyl)butyl]-2-pyrrolidinyl}methyl)pyrido[3,4-d]pyridazin-1(2H)-one Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Histamine H1 receptor Protein (Entity type)	Kd
4-[(4-Chlorophenyl)methyl]-2-({(2R)-1-[4-(4-{[3-(hexahydro-1H-azepin-1-yl)propyl]oxy}phenyl)butyl]-2-pyrrolidinyl}methyl)pyrido[3,4-d]pyridazin-1(2H)-one Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Potassium voltage-gated channel subfamily H member 2 Protein (Entity type)	IC50
4-[(4-Chlorophenyl)methyl]-2-({(2R)-1-[4-(4-{[3-(hexahydro-1H-azepin-1-yl)propyl]oxy}phenyl)butyl]-2-pyrrolidinyl}methyl)pyrido[3,4-d]pyridazin-1(2H)-one Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Histamine H3 receptor Protein (Entity type)	Ki
4-[(4-Chlorophenyl)methyl]-2-({(2R)-1-[4-(4-{[3-(hexahydro-1H-azepin-1-yl)propyl]oxy}phenyl)butyl]-2-pyrrolidinyl}methyl)pyrido[3,4-d]pyridazin-1(2H)-one Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Alpha-1A adrenergic receptor Protein (Entity type)	Ki

4-[(4-Chlorophenyl)methyl]-2-({(2R)-1-[4-(4-{[3-(hexahydro-1H-azepin-1-yl)propyl]oxy}phenyl)butyl]-2-pyrrolidinyl}methyl)pyrido[3,4-d]pyridazin-1(2H)-one
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Alpha-1B adrenergic receptor
Protein (Entity type)
Ki

4-[(4-Chlorophenyl)methyl]-2-({(2R)-1-[4-(4-{[3-(hexahydro-1H-azepin-1-yl)propyl]oxy}phenyl)butyl]-2-pyrrolidinyl}methyl)pyrido[3,4-d]pyridazin-1(2H)-one
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Histamine H1 receptor
Protein (Entity type)
Kd

4-[(4-Chlorophenyl)methyl]-2-({(2R)-1-[4-(4-{[3-(hexahydro-1H-azepin-1-yl)propyl]oxy}phenyl)butyl]-2-pyrrolidinyl}methyl)pyrido[3,4-d]pyridazin-1(2H)-one
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Potassium voltage-gated channel subfamily H member 2
Protein (Entity type)
IC50

4-[(4-Chlorophenyl)methyl]-2-({(2R)-1-[4-(4-{[3-(hexahydro-1H-azepin-1-yl)propyl]oxy}phenyl)butyl]-2-pyrrolidinyl}methyl)pyrido[3,4-d]pyridazin-1(2H)-one
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Histamine H3 receptor
Protein (Entity type)
Ki

4-[(4-Chlorophenyl)methyl]-2-({(2R)-1-[4-(4-{[3-(hexahydro-1H-azepin-1-yl)propyl]oxy}phenyl)butyl]-2-pyrrolidinyl}methyl)pyrido[3,4-d]pyridazin-1(2H)-one
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Alpha-1A adrenergic receptor
Protein (Entity type)
Ki

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