2-chloro-4-((7R,7aS)-7-hydroxy-1,3-dioxo-tetrahydro-1H-pyrrolo[1,2-e]imidazol-2(3H)-yl)-3-methylbenzonitrile (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 2-chloro-4-((7R,7aS)-7-hydroxy-1,3-dioxo-tetrahydro-1H-pyrrolo[1,2-e]imidazol-2(3H)-yl)-3-methylbenzonitrile's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
2-chloro-4-((7R,7aS)-7-hydroxy-1,3-dioxo-tetrahydro-1H-pyrrolo[1,2-e]imidazol-2(3H)-yl)-3-methylbenzonitrile Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	NXN Gene (Entity type)	-0.0059046843
2-chloro-4-((7R,7aS)-7-hydroxy-1,3-dioxo-tetrahydro-1H-pyrrolo[1,2-e]imidazol-2(3H)-yl)-3-methylbenzonitrile Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	AMIGO2 Gene (Entity type)	-0.0053979275
2-chloro-4-((7R,7aS)-7-hydroxy-1,3-dioxo-tetrahydro-1H-pyrrolo[1,2-e]imidazol-2(3H)-yl)-3-methylbenzonitrile Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SPP1 Gene (Entity type)	-0.005682605
2-chloro-4-((7R,7aS)-7-hydroxy-1,3-dioxo-tetrahydro-1H-pyrrolo[1,2-e]imidazol-2(3H)-yl)-3-methylbenzonitrile Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	KDM5D Gene (Entity type)	-0.0050259875
2-chloro-4-((7R,7aS)-7-hydroxy-1,3-dioxo-tetrahydro-1H-pyrrolo[1,2-e]imidazol-2(3H)-yl)-3-methylbenzonitrile Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DEGS1 Gene (Entity type)	-0.007115464
2-chloro-4-((7R,7aS)-7-hydroxy-1,3-dioxo-tetrahydro-1H-pyrrolo[1,2-e]imidazol-2(3H)-yl)-3-methylbenzonitrile Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HEY1 Gene (Entity type)	0.004079095
2-chloro-4-((7R,7aS)-7-hydroxy-1,3-dioxo-tetrahydro-1H-pyrrolo[1,2-e]imidazol-2(3H)-yl)-3-methylbenzonitrile Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	2,6-Di-tert-butyl-4-[1-(3,5-di-tert-butyl-4-hydroxy-phenylsulfanyl)-1-methyl-ethylsulfanyl]-phenol::2,6-di(tert-butyl)-4-{1-[3,5-di(tert-butyl)-4-hydroxyphenylsulfanyl]-1-methylethylsulfanyl}phenol::2,6-di(tert-butyl)-4-{1-[3,5-di(tert-butyl)-4-hydroxyphenylsulfanyl]-1-methylethylsulfanyl}phenol(probucol)::2,6-di-tert-butyl-4-(2-(3,5-di-tert-butyl-4-hydroxyphenylthio)propan-2-ylthio)phenol::CHEMBL608::DH-581::Lorelco::PROBUCOL::US9182402, 14 Compound (Entity type)	0.368582546710968
2-chloro-4-((7R,7aS)-7-hydroxy-1,3-dioxo-tetrahydro-1H-pyrrolo[1,2-e]imidazol-2(3H)-yl)-3-methylbenzonitrile Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MTCL1 Gene (Entity type)	-0.004169426
2-chloro-4-((7R,7aS)-7-hydroxy-1,3-dioxo-tetrahydro-1H-pyrrolo[1,2-e]imidazol-2(3H)-yl)-3-methylbenzonitrile Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SCGB1D2 Gene (Entity type)	-0.004554114
2-chloro-4-((7R,7aS)-7-hydroxy-1,3-dioxo-tetrahydro-1H-pyrrolo[1,2-e]imidazol-2(3H)-yl)-3-methylbenzonitrile Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	EIF1AY Gene (Entity type)	-0.0043711415