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Navitoclax (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Navitoclax's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	Navitoclax Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	H2BC5 Gene (Entity type)	-0.0039008444
	Navitoclax Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HMGA2 Gene (Entity type)	0.0038730314
	Navitoclax Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Bcl-2-like protein 1 Protein (Entity type)	Ki
	Navitoclax Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CXCL14 Gene (Entity type)	0.003805572
	Navitoclax Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NPY1R Gene (Entity type)	0.0037770728
	Navitoclax Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Bcl-2-like protein 2 Protein (Entity type)	IC50
	Navitoclax Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SFRP1 Gene (Entity type)	0.003832689
	Navitoclax Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PLK1 Gene (Entity type)	0.003476566
	Anagrelide Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Navitoclax Compound (Entity type)	0.4335359930992126
	Navitoclax Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PHYH Gene (Entity type)	-0.003772492

Navitoclax
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
H2BC5
Gene (Entity type)
-0.0039008444

Navitoclax
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
HMGA2
Gene (Entity type)
0.0038730314

Navitoclax
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Bcl-2-like protein 1
Protein (Entity type)
Ki

Navitoclax
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CXCL14
Gene (Entity type)
0.003805572

Navitoclax
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
NPY1R
Gene (Entity type)
0.0037770728

Navitoclax
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Bcl-2-like protein 2
Protein (Entity type)
IC50

Navitoclax
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SFRP1
Gene (Entity type)
0.003832689

Navitoclax
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PLK1
Gene (Entity type)
0.003476566

Anagrelide
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Navitoclax
Compound (Entity type)
0.4335359930992126

Navitoclax
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PHYH
Gene (Entity type)
-0.003772492

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