ATF5 (Gene)

Description: activating transcription factor 5

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View ATF5's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with ATF5.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using ATF5.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for ATF5.

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Gene Sets (494)

LINCS L1000 Chem Pert Consensus Sigs (384)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (1)

A gene set library provided by IDG

LINCS L1000 CRISPR KO Consensus Sigs (100)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (4)

A gene set library provided by MoTrPAC

GTEx Tissues V8 2023 (5)

A gene set library provided by GTEx

Knowledge Graph Assertions

Source	Relation	Target	Evidence
SD-6-035-A8 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ATF5 Gene (Entity type)	0.008687033
L-778123 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ATF5 Gene (Entity type)	-0.006442162
5-(9-isopropyl-8-methyl-2-morpholino-9H-purin-6-yl)pyrimidin-2-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ATF5 Gene (Entity type)	-0.014149697
3-(4-(((2-(1H-indol-3-yl)ethyl)(2-hydroxyethyl)amino)methyl)phenyl)-N-hydroxyacrylamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ATF5 Gene (Entity type)	-0.011667919
idarubicin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ATF5 Gene (Entity type)	0.010586026
Entinostat Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ATF5 Gene (Entity type)	-0.011750035
Temefos Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ATF5 Gene (Entity type)	-0.007738736
WT-171 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ATF5 Gene (Entity type)	-0.014297533
tert-butyl N-[4-[3-[[7-(hydroxyamino)-7-oxo-heptyl]carbamoyl]isoxazol-5-yl]phenyl]carbamate Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ATF5 Gene (Entity type)	-0.019623427
isoguvacine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ATF5 Gene (Entity type)	0.0049335873