ORC1 (Gene)

Description: origin recognition complex subunit 1

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View ORC1's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with ORC1.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using ORC1.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for ORC1.

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Gene Sets (1000)

LINCS L1000 Chem Pert Consensus Sigs (449)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (7)

A gene set library provided by IDG

KOMP2 Mouse Phenotypes 2022 (8)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (531)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (2)

A gene set library provided by MoTrPAC

GTEx Tissues V8 2023 (3)

A gene set library provided by GTEx

Knowledge Graph Assertions

Source	Relation	Target	Evidence
Enrofloxacin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ORC1 Gene (Entity type)	0.0077766534
Ataluren Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ORC1 Gene (Entity type)	0.0033776027
eperezolid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ORC1 Gene (Entity type)	-0.0041023493
avagacestat Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ORC1 Gene (Entity type)	0.0039860737
methazolamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ORC1 Gene (Entity type)	0.004138878
3-(6-(4-(trifluoromethoxy)phenylamino)pyrimidin-4-yl)benzamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ORC1 Gene (Entity type)	0.0036693548
Minoxidil Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ORC1 Gene (Entity type)	0.0029968864
SID11112338 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ORC1 Gene (Entity type)	0.0033699754
agomelatine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ORC1 Gene (Entity type)	0.0039253915
Zaltoprofen Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ORC1 Gene (Entity type)	0.0050842674