NKX2-1 (Gene)

Description: NK2 homeobox 1

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View NKX2-1's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with NKX2-1.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using NKX2-1.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for NKX2-1.

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Gene Sets (924)

LINCS L1000 Chem Pert Consensus Sigs (397)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (3)

A gene set library provided by IDG

LINCS L1000 CRISPR KO Consensus Sigs (499)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (10)

A gene set library provided by GTEx

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (3)

A gene set library provided by MoTrPAC

GTEx Tissues V8 2023 (12)

A gene set library provided by GTEx

Knowledge Graph Assertions

Source	Relation	Target	Evidence
BG-1016 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NKX2-1 Gene (Entity type)	0.019043835
4-(6-(4-isopropoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-yl)quinoline Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	NKX2-1 Gene (Entity type)	-0.024821555
miglitol Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	NKX2-1 Gene (Entity type)	-0.0033080047
SEW-00445 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NKX2-1 Gene (Entity type)	0.009450462
Proguanil Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NKX2-1 Gene (Entity type)	0.004309974
Memantine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NKX2-1 Gene (Entity type)	0.006768331
usnic-acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NKX2-1 Gene (Entity type)	0.015985878
hemado Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	NKX2-1 Gene (Entity type)	-0.0109662665
Altizide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NKX2-1 Gene (Entity type)	0.008557222